腔隙性脑梗死伴发焦虑、抑郁的中医证候研究  

Study on the Characteristics of TCM Syndrome of the Accompanied Anxiety/Depression in Cerebral Lacunar Infarction

作　　者：韩振蕴[1] 苏芮[2] 扎娃[1] 范吉平[3] 

机构地区：[1]北京中医药大学东方医院神经内科 [2]北京中医药大学东直门医院神经内科 [3]中国中医科学院

出　　处：《中医杂志》2009年第8期730-731,739,共3页Journal of Traditional Chinese Medicine

摘　　要：目的研究腔隙性脑梗死(LI)伴发焦虑、抑郁的中医证型分布特征。方法将依据公认的诊断标准和辅助量表筛选的LI患者分为LI伴发焦虑抑郁组、单纯LI组,采取病例对照研究,进行量表评分和证候学观察。结果共收集到符合LI诊断的患者43例,其中LI伴发焦虑或抑郁的患者26例,占60.5%,单纯LI患者17例,占39.5%。两组患者中医证候分布无明显差别(P>0.05)。Logistic回归分析结果显示,阴虚阳亢证、血虚证与LI后抑郁的发生相关,阴虚阳亢证与LI后焦虑相关。结论单纯LI与LI后焦虑、抑郁的中医证候分布无明显差别,LI后抑郁多见阴虚阳亢证与血虚证,LI后焦虑多见阴虚阳亢证。Objective To explore the TCM symptom and distribution characteristics of anxiety/depression after cerebral lacunar infarction （LI）. Methods LI patients were selected based on recognized diagnosis criteria, and were divided into two groups, and observation group consisting of LI patients complicated with anxiety or depression and a control group of simple LI patients. The case- control study was carried out for the scale scoring and syndrome observation. Results Totally 43 LI patients were included 17 （39. 5 %） in the control group and 26 （60. 5 %） in the observation group. There was no statistic difference between two groups in terms of occurring frequencies of each syndrome （P〉 0.05）. Logistic regression analysis showed that yin deficiency with yang hyperactivity syndrome and blood deficiency syndrome were related with depression and yin deficiency with yang hyperactivity syndrome with anxiety. Conclusion Simple LI and LI accompanied by anxiety/depression showed no difference in distribution of TCM syndromes. Yin deficiency with yang hyperactivity syndrome is common in LI accompanied by anxiety. Both blood deficiency and yin deficiency with yang hyperactivity syndrome are common in LI accompanied by depression.

关 键 词：腔隙性脑梗死 焦虑 抑郁 证候 阴虚阳亢 血虚 

分 类 号：R277.7[医药卫生—中医学]