心肌缺血预适应对老年急性心肌梗死患者近期病死率的影响  

The pre-adaptation influence of myocardial ischemia on near-term mortality rate of acute myocardial infarction elderly

作　　者：高太有[1] 彭侃夫[1] 余洪军[1] 尹秋霞[2] 张世国[2] 

机构地区：[1]济南军区总医院老年病科,济南250031 [2]济南军区总医院检验科

出　　处：《中国老年学杂志》1998年第4期205-207,共3页Chinese Journal of Gerontology

基　　金：济南军区卫生部科技发展基金

摘　　要：目的探讨心肌缺血预适应对老年急性心肌梗死（AMI）患者近期病死率的影响．方法对照分析33例有心肌缺血预适应老年AMI患者（A组）与22例无心肌缺血预适应老年AMI患者（B组）的临床资料。结果A组肌酸磷酸激酶（CPK）与肌酸磷酸激酶同功酶MB（CK-MB）峰值、泵功能障碍发生率及近期死亡率均显著低于B组（P＜0．05～0．01）。结论CPK与CK-MB峰值的降低，提示心肌缺血预适应有缩小心肌梗死范围的作用；由于梗死范围缩小，故泵功能障碍发生率降低，这是使有心肌缺血预适应老年AMI患者近期病死率降低的主要原因。Objective Influence on near-term mortality rate by ischemic pre-adaptation in aged patients with acute myocardial infarction(AM) was studied. Methods The clinical data of 33 elderly AMI patients by ischendc pre-adaptation(group A) and 22 elderly patients without pre-adaptation(group B) were compared. Results Peak level of serum CPK and CPK-MB;incidence of cardiac pump function disturbance and near-term mortality rate in group A were significantly lower than that in the group B(P<0.05~0. 01). beclusions It is suggested that the infarct size was liwhted by pre-adaptation. The incidence of cardiac pumP function disturbance was reduced and the near-term mortality rate decreased.

关 键 词：心肌缺血 预适应 近期病死率 老年人 心肌梗塞 

分 类 号：R542.220.2[医药卫生—心血管疾病]