改良的追赶生长大鼠模型生物学特征的动态观察  

Dynamic changes of biological characteristics in modified catch-up growth rat model

作　　者：陈璐璐[1] 胡祥[1] 郑涓[1] 曾天舒[1] 张皎月[1] 邓秀玲[1] 视素萍[1] 孔雯[1] 张好好[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院内分泌科,武汉430022

出　　处：《中华内分泌代谢杂志》2009年第4期438-440,共3页Chinese Journal of Endocrinology and Metabolism

基　　金：国家自然科学基金资助项目（30771035）

摘　　要：动态观察改良的追赶生长大鼠模型生物学特征，发现该模型主要表现为：热卡限制期体重；体长生长抑制，恢复饮食后体重、体长、内脏脂肪快速增长，能量利用率一过性升高，与人群追赶生长变化相似，可作为一种较为理想的追赶生长研究平台。The dynamic changes of biological features in catch-up growth rats were observed. The results demonstrated that the animal model of catch-up growth achieved by way of refeeding after caloric restriction manifested rapid growth after temporary growth retardation, transiently increased food efficiency, and a faster growth rate of visceral adipose tissue versus body weight after nutritional rehabilitation. These findings are consistent with the characteristics of human catch-up growth.

关 键 词：追赶生长 热卡限制 营养提升 体脂 能量利用率 

分 类 号：R686[医药卫生—骨科学]