急性氯乙酸中毒研究进展  

Research progress on acute chloroacetic acid poisoning

作　　者：朱秋鸿[1] 黄金祥[1] 孟聪申[1] 

机构地区：[1]中国疾病预防控制中心职业卫生与中毒控制所,北京100050

出　　处：《中国工业医学杂志》2009年第4期275-278,共4页Chinese Journal of Industrial Medicine

基　　金：卫生部卫生标准课题

摘　　要：氯乙酸是一种重要的有机化工原料,对皮肤有很强的腐蚀性,可经呼吸道、消化道及破损的皮肤吸收,引起脑、心、肝、肾和肺等多脏器损害;其确切的发病机制目前尚不清楚。急性氯乙酸中毒目前尚无特效解毒剂,临床以清除毒物、对症支持治疗为主。Chloroacetic acid is an important chemical material, extensively used in the organic-chemistry industry. It has strong corrosiveness, can be well absorbed through respiratory tract, digestive tract and damaged skin, and induce obvious inju- ries of brain, heart, liver, kidney and lung. However, the pathogenic mechanism still remained unclear. No specific antidote is available in the treatment of acute chloroacetic acid poisoning. Immediate decontamination, symptomatic and supporting treatment are the common therapy in the clinical practice.

关 键 词：氯乙酸 中毒 发病机制 治疗 

分 类 号：R135.1[医药卫生—劳动卫生]