高压氧治疗一氧化碳中毒后迟发性神经病变的疗效观察  

Hyperbaric oxygen therapy in acute carbon monoxide poisoning with delayed encephalopathy:A clinical ob- servation of 63 cases

作　　者：于建敏[1] 何云[1] 张树新[2] 耿纪录[1] 闫学锋[1] 

机构地区：[1]解放军总医院第二附属医院门诊部,北京100091 [2]解放军总医院高压氧科,北京100091

出　　处：《疑难病杂志》2009年第10期591-592,共2页Chinese Journal of Difficult and Complicated Cases

摘　　要：目的观察高压氧治疗一氧化碳中毒后迟发性神经病变的疗效。方法63例一氧化碳中毒后迟发性神经病变患者(轻型32例,中型21例,重型10例),在病程不同阶段(1个月以内,1～3个月,3～6个月)分别接受高压氧治疗,观察其疗效并进行对比分析。结果63例患者经高压氧治疗平均(16±4)次,治愈28例(44.4%),显效21例(33.3%),有效9例(14.3%),无效5例(8.0%),总有效率92.0%。开始高压氧治疗越早,分型越轻,疗效越显著(P<0.05)。结论早期高压氧治疗对一氧化碳中毒后迟发性神经病变有显著疗效。Objective To investigate clinical effects in patients with delayed encephalopathy due to acute carbon monoxide poisoning. Methods Sixty three carbon monoxide poisoning in different stages （32 cases with mild type ,21 cases with moderate type and 10 cases with severity type） with delayed encephalopathy underwent hyperbaric oxygen therapy at different time of pathogenesis, including less than 1 m, 1 - 3 m and 3 - 6 m. The therapeutic effects were evaluated and analyzed. Results Hyperbaric oxygen therapy was applied average （ 16 ± 4 ） times in 63 cases, and 28（44.4% ） cases of them were recovered completely, 21 （33.3%） cases of them recovered significantly, 9 （ 14.3% ） cases of them recovered partially, and total effective rate was 92.0%. The more early received hyperbaric therapy, the more positive effects. Conclusion It demonstrated that early hyperbaric oxygen treatment would play an important role in preventing delayed encephalopathy caused by acute carbon monoxide poisoning.

关 键 词：一氧化碳中毒 迟发性神经病变 高压氧治疗 

分 类 号：R595.1[医药卫生—内科学] R747.9[医药卫生—临床医学]