STUDY ON NUCLEAR MATRIX PROTEINS FROM HUMAN BREAST CARCINOMA  

作　　者：何谦 张淑群 楚雍烈 贾晓黎 姜建涛 

机构地区：[1]Department of Clinical Lab, Second Affiliated Hospital of Medical School, Xi'an Jiaotong University [2]Department of Oncology, Second Affiliated Hospital of Medical School, Xi'an Jiaotong University [3]Department of Immunology and Microbiology, Xi'an Jiaotong University [4]Department of Infectious Disease, Second Affiliated Hospital of Medical School, Xi'an Jiaotong University

出　　处：《Journal of Shanghai Second Medical University(Foreign Language Edition)》2009年第2期73-76,共4页上海第二医科大学学报（英文版）

基　　金：Supported by the National Natural Science Foundation of China (No.30500600)

摘　　要：Objective To investigate the marker protein of human breast carcinoma from nuclear matrix proteins (NMPs). Methods NMPs were injected subcutaneously into rabbit to get antiserum, which was used to detect the NMPs specificity for breast carcinoma. Results There was an apparent positive band (100 kD) in the NMPs of breast carcinoma, which did not exist in normal breast and other tumors that were detected.Conclusion One or one group of 100 kD NMPs were found to be related to human breast carcinoma, which may be involved in the carcinogenesis and development of human breast carcinoma and valuable for breast carcinoma diagnosis.Objective To investigate the marker protein of human breast carcinoma from nuclear matrix proteins （NMPs）. Methods NMPs were injected subcutaneously into rabbit to get antiserum, which was used to detect the NMPs specificity for breast carcinoma. Results There was an apparent positive band （100 kD ） in the NMPs of breast carcinoma, which did not exist in normal breast and other tumors that were detected. Conclusion One or one group of 100 kD NMPs were found to be related to human breast carcinoma, which may be involved in the carcinogenesis and development of human breast carcinoma and valuable for breast carcinoma diagnosis.

关 键 词：breast carcinoma nuclear matrix proteins tumor marker 

分 类 号：S855.3[农业科学—临床兽医学] Q279[农业科学—兽医学]