EFFECTS OF SLEEP DEPRIVATION ON WHOLE NIGHT POLYSOMNOGRAPHY IN HEALTHY YOUNG MEN  

作　　者：肖泽萍 陈兴时 王继军 张明岛 王红星 胡珍玉 路英智 张载福 甘景梨 楼翡璎 陈冲 张天宏 范青 

机构地区：[1]Department of Electrophysiology, Shanghai Mental Health Center, Shanghai Jiaotong University

出　　处：《Journal of Shanghai Second Medical University(Foreign Language Edition)》2009年第2期77-80,共4页上海第二医科大学学报（英文版）

基　　金：Supported by National High Technology Research and Development Program of China (863 Program, No.2007AA02Z420 and No.2008AA02Z412);Joint Key Project of New Frontier Technology in Shanghai Municipal Hospitals (No.SHDC12006105);Foundation of the National Natural Science Foundation of China (No.30770772);the Municipal Committee of Shanghai Science and Technology (No.09411968200)

摘　　要：Objective To assess the effects of sleep deprivation (SD) on the whole night polysomnography (PSG) in healthy young men. Methods The whole night PSG was recorded by using Neurofax-1518K (Nihon Kohden, Japan) system before and after 38 h of SD among 15 healthy male subjects. Results Compared with PSG before SD, post-SD PSG showed significantly shortened sleep latency (before SD: 19.7±9.3, after SD: 5.6±7.3, P<0.05), decreased stage 1 (S1) non-rapid eye movement (NREM) sleep [before SD: (9.2±1.9)%, after SD: (4.0±1.4)%, P<0.05], and increased stage 4 (S4) NREM sleep [before SD: (10.3±3.7)%, after SD: (26.2±4.3)%, P<0.01]. Conclusion During post-SD sleep, the proportion of S4 NREM sleep was increased as compensation in healthy male. In addition, SD was proved to affect electrophysiological brain activities in normal people.Objective To assess the effects of sleep deprivation （SD） on the whole night polysomnography （PSG） in healthy young men. Methods The whole night PSG was recorded by using Neurofax-1518K （ Nihon Kohden, Japan） system before and after 38 h of SD among 15 healthy male subjects. Results Compared with PSG before SD, post-SD PSG showed significantly shortened sleep latency （before SD. 19.7 ± 9. 3, after SD： 5.6± 7.3, P 〈 0. 05 ） , decreased stage 1 （ S1 ） non-rapid eye movement （NREM） sleep [ before SD： （ 9. 2 ± 1.9 ） % , after SD： （4.0 ± 1.4 ） %, P 〈 0. 05 ], and increased stage 4 （ S4 ） NREM sleep [ before SD ： （ 10. 3 ± 3.7 ） %, after SD ： （ 26. 2 ± 4. 3 ） %, P 〈 0. 01 ]. Conclusion During post-SD sleep, the proportion of S4 NREM sleep was increased as ＂ compensation＂ in healthy male. In addition, SD was proved to affect electrophysiological brain activities in normal people.

关 键 词：sleep deprivation polysomnography 

分 类 号：Q428[生物学—神经生物学] C913.1[生物学—生理学]