复方硫酸亚铁缓释片的制备工艺优化  

Preparation of ferrous sulfate sustained-release tablets

作　　者：刘燕[1] 王贺[1] 柏俊[1] 孙备[1] 

机构地区：[1]安徽省药物研究所安徽省药物缓控释技术工程研究中心,安徽合肥230022

出　　处：《安徽医药》2009年第8期875-876,共2页Anhui Medical and Pharmaceutical Journal

摘　　要：目地研究复方硫酸亚铁缓释片的制备方法。方法采用正交试验设计,考察石蜡、氢化植物油、羟丙基甲基纤维素对复方硫酸亚铁缓释片质量指标的影响。结果采用石蜡可满足产品质量要求。结论石蜡与其他辅料相比,有较好的性价比,可有效降低生产成本,该处方质量稳定,合理、可行。Aim To study the preparation method of ferrous sulfate sustained-release tablets.Methods The orthogonal design was carried out to compare the effect on quality parameters of ferrous sulfate sustained-release tablets among paraffin,oil hydrogenation and hydroxypropyl methyl cellulose.Result Paraffin is up to the mustard of the product quality.Conclusion Compared with the other supplementary materials,paraffin can effectively decrease the cost of production and ensure the steady quality.The technology is feasible and reasonable.

关 键 词：复方硫酸亚铁缓释片 石蜡 正交试验设计 

分 类 号：TQ463[化学工程—制药化工]