柳州地区育龄妇女孕前TORCH感染筛查及补气解毒汤治疗临床探讨  

Clinical investigation of pre-pregnant TORCH infection screening among childbearing aged women in Liuzhou and the effect of Bu Qi Jie Du Soup on TORCH infection

作　　者：区绮文 王琼[2] 莫可良[2] 陈少卿[2] 罗玉芳[2] 李敏[2] 覃红 邱劼 王茜 

机构地区：[1]广西柳州市人口和计划生育服务中心,柳州545001 [2]广西医科大学第四附属医院,柳州545005

出　　处：《中国临床新医学》2009年第8期794-797,共4页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

基　　金：柳州市科技基金资助项目(编号:200721304)

摘　　要：目的探讨柳州地区育龄妇女孕前妊娠早期病原体感染（TORCH）感染发病率，寻找降低TORCH感染综合征的有效药物。方法通过ELISA法对柳州地区2305例育龄妇女进行血清TORCH特异性抗体IgM（TORCH—IgM）筛查，将150例TORCH—IgM筛查阳性患者分为观察组（85例）和对照组（85例），观察组采用中药补气解毒汤治疗，对照组采用常规西药治疗，分析比较两组患者治疗效果。结果柳州地区TORCH感染的阳性率为7．38％，其中CMV、TOX、RV、HSV—I及HSV-U的阳性检出率分别为3．90％、1．82％、1．04％、0．35％、0．26％，不同病原体之间其感染率差别有统计学意义（P〈0．05），CMV感染率最高；观察组和对照组疗效比较差别无统计学意义（P〉0．05），补气解毒汤治疗TORCH感染与西药治疗的疗效相同。结论本次旨在了解柳州地区育龄妇女孕前TORCH感染发病率，这对指导柳州地区今后的优生工作有重要意义；补气解毒汤治疗TORCH感染综合征与西药治疗的疗效相同，但补气解毒汤可同时抵抗多种病毒感染，且缩短了疗程，未发现毒副作用，经济实用，是预防和减少不良妊娠发生的有效方法，值得临床推广应用。Objective To investigate the prevalence of TORCH infection among childbearing aged women in Liuzhou and the medicine for TORCH infection syndrome. Methods A total number of 2 305 cases received serum test for TORCH-IgM antibody with ELISA techniques, 170 cases were randomly selected from the positive restdts which were divided into observe group （85 cases） and control group （ 85 cases）, Bu Qi Jie Du Soup treatment was uesd in observe group, another group adopted common Western medicine, the difference between these two groups were analysed. Results The positive rate of TORCH infection was 7.38% in Liuzhou, the positive rates of IgM for CMV,TOX,RV.HSV- Ⅰ ,and HSV- Ⅱ were 3.90%, 1.82%, 1.04%, 0. 35% and 0. 26% respectively, there was statistical significance in the differences of infection rate in different pathogens （ P 〈 0. 05 ） , CMV was the first in TORCH prevalence;There was no statistical significance in the differences of curative effect between observe group and control group（P〉0. 05）, Bu Qi Jie Dn Soup treatment for TORCH infection had the same curative effect with common Western medicine treatment. Conclusion The study of the prevalence of TORCH infection among childbearing aged women in Liuzhou is helpful to guide the aristogenesis works in liuzhou; Bu Qi Jie Du Soup treatment is against several kinds of virus infection, and the time of treatment shortened, it is effective in preventing or reducing bad pregnancy, it is worth to extend and apply in clinical work.

关 键 词：TORCH感染 孕前 中药 补气解毒汤 

分 类 号：R511[医药卫生—内科学] R531[医药卫生—临床医学]