戊型病毒性肝炎研究进展  

Study Progress on Hepatitis E

作　　者：吴婷[1] 江浪[1] 

机构地区：[1]厦门大学生命科学学院,国家传染病诊断试剂与疫苗工程技术研究中心,福建厦门361005

出　　处：《中国疫苗和免疫》2009年第4期375-378,共4页Chinese Journal of Vaccines and Immunization

摘　　要：戊型病毒性肝炎(戊肝)约占临床急性散发性病毒性肝炎的10%～20%,病死率约0.5%～1.5%,孕妇戊肝病人的病死率可高达20%。中国是戊肝的高流行区。戊肝病毒主要通过肠道传播,亦有证据表明可以通过血液传播。近年来,随着对戊肝病原学、流行病学研究的深入开展,诊断试剂及疫苗研发进展迅速,现对戊肝的流行病学、诊断学及疫苗研究作一综述。10%～20% of acute clinical sporatic hepatitis is hepatitis E （HE）. HE has a severe diaease low mortality in general population of about 0.5～1.5%. It has been reported as severe disease and the mortality increased to 20% in pregnant women and old people. China is high-epidemic for hepatitis E virus （HEV）. HEV is mainly transmitted through faecaloral route,data also showed that HEV could be transferred through blood donation. The epidemiology,diagnostics and vaccine development of HE is reviewed in this paper.

关 键 词：戊型病毒性肝炎 戊型肝炎病毒 诊断试剂 疫苗 临床试验 

分 类 号：R512.6[医药卫生—内科学]