ICP-AES法测定广西产中药广豆根及千斤拔中的金属元素含量  

Determination of Metal Contents of Two Chinese Medicinal Herbs,Flemingiae Philippinensis and Sophora Tonkinensis,Grown inGuangxi by ICP-AES

作　　者：毛俐[1,2] 谭明雄[1] 陈振锋[1] 梁宏[1] 

机构地区：[1]广西师范大学化学化工学院,药用资源化学与药物分子工程教育部重点实验室,广西桂林541004 [2]西华师范大学化学化工学院,四川南充637002

出　　处：《光谱学与光谱分析》2009年第9期2568-2570,共3页Spectroscopy and Spectral Analysis

基　　金：国家自然科学基金项目(30460153,3026002,20861002);教育部新世纪优秀人才支持计划项目(NCET-04-0836);广西科技计划应用基础研究专项经费项目(0575046);广西“新世纪十百千人才工程”项目(2003223)资助

摘　　要：采用湿法消解制样,运用ICP-AES法对广西产中药广豆根和千斤拔中的常量及微量金属元素的含量进行了测定。研究了仪器的工作条件,各元素的分析线和检测限,元素的含量平均值和标准差。结果表明广豆根中含Cu,Zn,Fe,Mn,Cr等微量金属元素和Ca,Mg,Na,K常量金属元素;千斤拔中含Cu,Zn,Fe,Ni,Mn,Cr等微量金属元素和Ca,Mg,Na,K常量金属元素;两者都不含Sn,Pb,Cd等对人体有害的元素。相对标准偏差值均小于5%。研究中还发现广豆根和千斤拔中Zn/Cu值分别为6.4和5.7左右,呈锌高铜低的现象,与癌症患者血清中锌低铜高的现象相反,而与抗癌中药中微量元素的含量锌高铜低的现象一致,这对理解这些抗癌中药的药理作用有一定的启示作用。The metal contents of traditional Chinese medicine, Sophora tonkinensis and Flemingiae philippinensis, grown in Guangxi province of China were determined by ICP-AES methods. The two herbs were digested by applying acid bomb digestion procedure. Considering RF power, nebulized gas flow rate, auxiliary gas flow rate and pump rate, the instrument was optimized. The instrument operating conditions, analytical lines and detection limits of elements determined as well as the contents of elements in these two herbs were reported. The results show that Sophora tonkinensis contains mieroelements Cu, Zn, Fe, Mn and Cr and macroelements Ca, Mg, Na and K; Flemingiae philippinensis contains microelements Cu, Zn, Fe, Ni, Mn and Cr and macroelements Ca, Mg, Na and K. However, the two traditional Chinese medicines do not contain toxic elements Sn, Pb and Cd. The precision was found to be less than 5 ~fro in terms of relative standard deviation mostly. The results indicate that the concentration ratio of zinc to copper in Sophora tonkinensis is 6.4, while the ratio in Flemingiae philippinensis is 5.7. The content of zinc is higher than copper in both two herbs, which agrees with the phenomenon that the zinc content higher than that of copper exists in other antitumor traditional Chinese medicine. All these will afford an apocalypse for understanding the pharmacological mechanism of these anitumor traditional Chinese medicines.

关 键 词：金属元素 ICP-AES 广豆根 千斤拔 

分 类 号：O657.3[理学—分析化学]