温度/pH敏感性接枝共聚物水凝胶P(DMAEMA-g-NIPAM)的合成及性质研究  

Synthesis and Characterization of Temperature- and pH-sensitive Poly[2-(N,N-dimethylamino)ethyl methacrylate-g-N-isopropylacrylamide] Hydrogels

作　　者：刘守信[1] 张朝阳[1] 房喻[1] 王焕霞[1] 陈奋强[1] 

机构地区：[1]应用表面与胶体化学教育部重点实验室陕西师范大学化学与材料科学学院,西安710062

出　　处：《化学学报》2009年第16期1910-1916,共7页Acta Chimica Sinica

基　　金：国家自然科学基金(No20674048)资助项目

摘　　要：利用大分子单体技术,采用自由基溶液聚合合成了温度/pH敏感性聚甲基丙烯酸-N,N-二甲氨基乙酯接枝聚N-异丙基丙烯酰胺[P(DMAEMA-g-NIPAM)]水凝胶.用红外光谱及扫描电镜对凝胶的组成及形貌进行了表征.凝胶的去溶胀和溶胀动力学研究表明,所合成的凝胶具有温度和pH敏感性.与传统的聚丙烯酸系水凝胶相比,P(DMAEMA-g-NIPAM)具有相反的pH敏感性;P(DMAEMA-g-NIPAM)凝胶在55℃时具有较快的去溶胀速率,随着凝胶中接枝链PNIPAM量的增加,凝胶的去溶胀速率加快.A novel temperature- and pH-sensitive graft copolymer hydrogel composed of 2-（N,N- dimethylamino）ethyl methacrylate （DMAEMA） and N-isopropylacrylamide （NIPAM） was synthesized by macromonomer technique and free radical solution polymerization. The composition and surface morphology of the hydrogels were investigated by means of Fourier transform infrared spectroscopy and scanning electron microscopy. The deswelling and swelling kinetics of the graft copolymer hydrogels in different pH media at different temperatures demonstrate that the graft copolymer hydrogels have temperature and pH double sensitivities. Compared with conventional polyacrylic acid hydrogels, the pH sensitivity of synthesized hydrogels is contrary and the hydrogels are in swollen state in acid medium. The P（DMAEMA-g-NIPAM） hydrogels have a faster deswelling rate at 55 ℃, and the more the PNIPAM graft chain contents in the hydrogels are, the faster the deswelling rate of the hydrogels is.

关 键 词：甲基丙烯酸-N N-二甲氨基乙酯 N-异丙基丙烯酰胺 接枝水凝胶 

分 类 号：O631.3[理学—高分子化学]