天然牛黄、培植牛黄和鸡胆汁对大鼠足跖肿胀率及炎性组织中PGE_2含量的影响  

Effects of Natural Cow-bezoar,Cultured Cow-bezoar and Chicken Bile on Rat Paw Edema and PGE_2 Content of Inflammatory Tissues of Rat

作　　者：李培锋[1] 张建华[2] 关红[1] 哈斯苏荣[1] 

机构地区：[1]内蒙古农牧学院动物医学系,呼和浩特010018 [2]内蒙古农牧学院生物工程系,呼和浩特010018

出　　处：《中草药》1998年第9期603-605,共3页Chinese Traditional and Herbal Drugs

基　　金：内蒙古自治区自然科学基金

摘　　要：采用大鼠足跖肿胀法和紫外可见分光光度法，研究了天然牛黄、胆红素含量不同的培植牛黄以及鸡胆汁对大鼠角叉菜胶性和甲醛性的足跖肿胀率和炎性组织中PGE2含量的影响。结果表明，天然牛黄，中胆红素培植牛黄、低胆红素培植牛黄和鸡胆汁均能显著地抑制角叉菜胶和甲醛致炎后的大鼠足跖肿胀和炎性组织中的PGE2含量。经F-检验，这4种中药的作用相互间差异无显著性。Effects of natural cow-bezoar,cultured cow-bezoar with different bilirubin content and chicken bile on rat paw edema induced by carrageenin and formaldehyde and the postaglandin E2 (PGE2) content of inflammatory tissues of rat were determined by foot-digitoplantar turgorneter and UV spectrophotometry. Results showed that natural cow-bezoar,cultured cow-bezoar,with medium or low bilirubin content and chicken bile(0.5 g/kg ig) could significantly inhibit rat paw edema induced by carrageenin and formaldehyde in rat.They also decreased the content of PGE2 in inflammatory tissues of rats,but results were not statistically significant when treated with F-test.

关 键 词：天然牛黄 培植牛黄 鸡胆汁 肿胀率 PGE2 药理 

分 类 号：R285.5[医药卫生—中药学] R282.740.5[医药卫生—中医学]