中药抗淋球菌的实验研究  

The experimental research of traditional Chinese medicine to Anti-Neisseria gonorrhoeae

作　　者：邓莘芸[1] 胡英辉[1] 程辉龙[1] 黄文长[2] 马细妹[2] 章志红[1] 石林波[2] 

机构地区：[1]南昌大学抚州医学分院,江西抚州344000 [2]南昌大学医学院病原生物学教研室,江西南昌330006

出　　处：《Journal of US-China Medical Science》2009年第8期32-33,38,共3页美中医学（英文版）

基　　金：本课题为2003年抚州市科技局立项课题（项目编号：030808）、南昌大学抚州医学分院课题.本课题的主要实验工作都由胡英辉主管技师完成.

摘　　要：目的寻找对耐青霉素、经临床分离流行性淋球菌有效抗菌的中药。方法采取双盲法，选用临床常用中药，以平板纸片定量加药法进行体外抑菌试验。结果平板纸片定量加药抑菌试验，结果发现高浓度（15mg）中药量有24味中药对淋球菌具有不同程度的抑制作用，对G1、G2、G3流行株淋球菌抑制作用较好的有21、13、5号中药，其中21号中药封淋球菌最具抑菌作用。结论21号等中药对耐药流行株淋球菌有不同程度的抑制作用。开发中药抗流行性淋球菌具有广阔的应用前景。Objective To find the effective Chinese medicine to resist the epidemic Neisseria gonorrhoeae, which is resistant to penicillin. Methods The commonly used Chinese medicine was selected to carry on vitro bacteriostasis experiment with quantitative medicine method of plate paper disc by adopting double-blind experiment. Results The results showed there were kinds of high concentration （15mg） Chinese Herbs on the Neisseria gonorrhoeae with varying degrees of inhibition, 21, 13, 5 traditional Chinese medicine had better inhibitory action on the G1, G2, G3 epidemic strains of Neisseria gonorrhoeae, of which, the 21 traditional Chinese medicines was the most antibacterial medicine for the gonococcus. Conclusion 21 etc kinds of traditional Chinese medicines have the varying degree inhibitory action on the epidemic Neisseria gonorrhoeae strains resistant to drug, and there is the broad application prospect in the development of traditional Chinese medicine anti-epidemic gonococcus.

关 键 词：中药 流行性淋球菌 体外抑菌试验 

分 类 号：R283[医药卫生—中药学] R392-33[医药卫生—中医学]