孟鲁司特治疗慢性支气管炎的临床观察  

Clinical observation on montelukast in chronic bronchitis

作　　者：赵本玉[1] 方明[1] 陈艳[2] 

机构地区：[1]淮南市第一人民医院呼吸科,安徽淮南232000 [2]淮南市第一人民医院药剂科,安徽淮南232000

出　　处：《安徽医药》2009年第10期1267-1268,共2页Anhui Medical and Pharmaceutical Journal

摘　　要：目的观察孟鲁司特治疗慢性支气管炎的疗效。方法36例慢性支气管炎患者在常规治疗同时口服孟鲁司特,每次10mg,每晚顿服,共用4周。随机选择34例作为对照组予常规治疗,观察患者咳、痰、喘的好转时间及住院时间,并随访6个月观察复发情况。结果口服孟鲁司特组,咳、痰、喘的好转时间短于对照组,(P<0.05);住院时间少于对照组,P<0.05,且可减少复发次数。结论口服孟鲁司特辅助治疗慢性支气管炎有较好疗效。Aim To observe the clinical effects of Montelukast in chronic bronchitis . Methods Thirty-six cases of chronic bronchitis were treated with Montelukast in addition to conventional therapy, 10 mg taken at a draught every evening for 4 weeks. Thirty-four cases of chronic bronchitis were random selected to compare with conventional therapy. We observed the in-hospital time and the remission time of cough, expectoration and asthma . The follow-up of 6 months were done to obtain the recurrence rate. Results The remission time of cough, expectoration and asthma in the trial group were shorter than control group, （ P 〈 0.05 ）, the recurrence rate of therapy group also lower than the control group. Conclusion The adjutant therapy through per os montelukast is significant in chronic bronchitis.

关 键 词：孟鲁司特 白三烯受体拮抗剂 慢性支气管炎 

分 类 号：R562.21[医药卫生—呼吸系统]