血清D-二聚体浓度对急性主动脉夹层的意义  

D - dimer in acute aortic dissection

作　　者：尹俊[1] 姚晨玲(综述)[1] 童朝阳(审校)[1] 

机构地区：[1]复旦大学附属中山医院急诊科,上海200032

出　　处：《中国急救医学》2009年第9期840-843,共4页Chinese Journal of Critical Care Medicine

摘　　要：血清D-二聚体是交联纤维蛋白的降解产物，可用来协助诊断深静脉血栓和肺栓塞。急性主动脉夹层（acuteaortic dissection，AAD）患者其D-二聚体浓度升高，提示D-二聚体可能为该病的一种生物学标志。研究证明，D-二聚体浓度对AAD患者的诊断、判断病变范围及预后均有一定的价值。D - dimer is a product of plasmin fibrinolysis of cross - linked fibrin. It has been proved serum D - dimer is a sensitive test in Deep Vein Thrombosis and Pulmonary Embolism. Some scientists have detected the elevation of D - dimer in patients with Acute aortic dissection, which suggests that D - dimer may be a biomarker of the disease which is lack of sensitive screening indicator in common use. According to the articles available, we finally draw the conclusion that D - dimer can provide valuable diagnostic and prognostic information of patients with Acute aortic dissection.

关 键 词：D-二聚体 急性主动脉夹层 深静脉血栓 肺栓塞 

分 类 号：R543.1[医药卫生—心血管疾病]