侧向氟代四环类液晶单体的合成  

Synthesis of Lateral Fluorine Substituted 4,4′-Bis-(trans-4-n-alkylcyclohexyl) Biphenyl Liquid Crystals

作　　者：李娟利[1] 安忠维[1] 杜渭松[1] 李建[1] 郑敏燕[2] 

机构地区：[1]西安近代化学研究所光电材料中心,陕西西安710065 [2]咸阳师范学院,陕西咸阳712000

出　　处：《化学世界》2009年第9期543-545,F0004,共4页Chemical World

摘　　要：以4-(反式-4-烷基环己基)-2-氟苯硼酸和卤代苯为起始原料,采用Suzuki偶联反应合成了2个系列15个侧向氟取代双烷基环己基联苯类液晶,采用1H NMR、IR和MS对其结构进行了确证。讨论了不同催化剂、反应底物量以及不同的碱对反应结果的影响,结果表明:在强碱碳酸钾作用下,Pd(PPh3)4作催化剂、4-(反式-4-烷基环己基)-2-氟代苯硼酸∶卤代苯(摩尔比)=1.1∶1时,反应选择性和收率较高,产品收率最高达89%。Two series of fifteen lateral fluorine substituted by 4,4＇-bis-（trans-4-n-alkylcyclohexyl）biphenyl liquid crystals were synthesized via Suzuki coupling reaction with 2-fluoro-4-（trans-4-alkylcyclohexyl） phenylboronic and halobenzenes as starting materials. Their structures were confirmed using ^1H NMR, IR and MS. The influence of various catalysts, various ratio of reactants and bases on the reaction was studied. The results showed that with Pd （PPh3.）4 as catalyst, 2-fluoro-4-（trans-4-alkyl＇cyclohexyl） phenylboronic： halobenzenes=1. 1 ： 1（mole ratio） and potassium carbonate as base was the best choice, and the best yield was 89%.

关 键 词：SUZUKI偶联反应 合成 液晶 

分 类 号：O621.3[理学—有机化学]