经穴强化埋线联合中药注入治疗磺脲类药物继发失效机理的研究  

Effects of Chinese Medicinal Injection Plus Catgut Implantation at Acupoint on Diabetics with Secondary Sulfonylureas Failure

作　　者：张力彪[1,2] 张存志 王素敏[1] 张瑞君 邸力强 曹瑞芳 邸正 

机构地区：[1]河北医科大学基础医学院药理教研室,河北石家庄050017 [2]河北省直属机关第二门诊部,河北石家庄050051 [3]赵县糖尿病研究所,河北赵县051530

出　　处：《辽宁中医杂志》2009年第9期1447-1449,共3页Liaoning Journal of Traditional Chinese Medicine

基　　金：河北省科技厅资助项目(07276101D-8)

摘　　要：目的:探讨经穴强化埋线联合应用中药治疗2型糖尿病患者磺脲类药物(SU)继发失效的发生机制。方法:将SU继发性失效2型糖尿病患者70例随机分为两组,治疗组38例,停用磺脲类口服降糖药物,在经穴强化埋线基础上加用中药治疗。对照组32例,单独应用中药注射液,疗程2个月。结果:两组患者治疗后空腹血糖(FBG)及餐后2h血糖(2hPBG)、糖化血红蛋白(HbA1 c)均得到较好控制,P<0.05和P<0.01;两组患者治疗后C肽均有升高,而治疗组升高更明显,P<0.05。结论:中药注射液联合应用经穴强化埋线优于单用中药疗法。可改善胰岛β细胞功能,提高血液C肽水平。Objective：To observe effects of Ch inesemedicinal injection plus catgut implantation at acupoint on diabetics with seeondary suffonylureas failure. Methods：70 patientsw ere randomly divided into a treatment group of 38 cases treated with Chi- nese medicinal injection plus catgutimp lantation at acupoint, and a control group of 32 cases treated with Chinese medicinal injec- tion. They were treated for 3 courses ,20 days constituting one course. Results：FBG,2hPBG and HbAle levels in treatment group were significandy improved（ P 〈 0.05 or P 〈 0. 01 ）. C-peptide in both groups were remarkably improved after treatment （P 〈0105 ）. Conclusion ： Chinese medicinal injection plus Catgut implantation at aeupoint can improve β-cell function of diabetics with secondary salfonylureas failure.

关 键 词：经穴强化埋线 磺脲类药物继发失效 Β细胞 C肽 

分 类 号：R244.8[医药卫生—针灸推拿学]