强直性脊柱炎患者血液流变学指标分析  

Analysis of Indexes of Hemorheology of Patients with Ankylosing Spondylitis

作　　者：许德英[1] 常永超[1] 程国平[1] 江涛[1] 岳彩娟[1] 

机构地区：[1]河南科技大学第一附属医院检验科,洛阳市471003

出　　处：《医药论坛杂志》2009年第16期20-21,共2页Journal of Medical Forum

摘　　要：目的对强直性脊柱炎患者的血液流变学检测指标进行分析,探讨强直性脊柱炎患者的血液流变学指标变化。方法对127例强直性脊柱炎患者组和130例健康对照组的血液流变学检查结果进行分析研究。结果强直性脊柱炎患者全血黏度、血浆黏度、血细胞压积、纤维蛋白原和红细胞沉降率方程K值均有显著增高(P<0.01),红细胞沉降率、红细胞聚集和刚性指数有不同程度升高(P<0.05),而红细胞变形和电泳指数有明显降低(P<0.05)。结论强直性脊柱炎患者有明显的血液流变学异常和微循环障碍,强直性脊柱炎患者血液流变学检测具有一定的临床价值,它可以反映病情严重程度及监测病情变化,并指导临床治疗。Objective To study the hemorheology examination parameters of patients with ankylosing spondylitis. spondylitis and to explore the hemorheology examination parameters change in ankylosing Methods Analysis on hemorheology examination results of 127 cases of patients and 130 cases of healthy controls. Results The patients, whole blood viscosity, plasm viscosity, hematocret, plasma fibrinogen and erythrocyte sedimentation rate k - equation were increased significantly （P 〈 0. 01 ）, erythrocyte sedimentation rate , erythrocyte aggregation and rigidity index were increased （P 〈 0. 05）, but erythrocytic deformation and electrophoresis index were decreased significantly （P 〈 0. 05）. Conclusion The hemorheology examination parameters of patients with ankylosing spondylitis were obviously abnormal, and there is a certain clinical value and can also intruct clinical treatment.

关 键 词：血液流变学 强直性脊柱炎 血液黏度 

分 类 号：R446.1[医药卫生—诊断学]