氟比洛芬酯对严重多发伤术后镇痛的临床研究  

The analgesic effect of flurbiprofen axetil on postoperative severe-multiple-trauma patients

作　　者：王一旻[1] 刘晓蓉[1] 刘云冬[2] 赵春香[2] 郑志芳[2] 陈君兰[2] 

机构地区：[1]天津泰达医院ICU,天津300457 [2]华北煤炭医学院附属医院

出　　处：《华北煤炭医学院学报》2009年第5期622-623,共2页Journal of North China Coal Medical College

摘　　要：①目的观察氟比洛芬酯用于严重多发伤术后镇痛有无相关获益。②方法对117例急诊全麻手术后的严重多发伤患者随机分组为芬太尼组和氟比洛芬酯复合小剂量芬太尼组,对比两组患者一般情况、病情、以及术后呼吸、意识恢复时间、拔管时间、芬太尼副作用发生率和用量。③结果在维持相同镇痛效果前提下,氟比洛芬酯复合小剂量芬太尼组术后呼吸意识恢复时间、拔管时间均短于芬太尼组,芬太尼副作用发生率和用量减少。④结论严重多发伤术后应用氟比洛芬酯镇痛可减少芬太尼用量,利于病情观察和尽早脱机拔管。Objective To study the analgesic effect of fiurbiprofen axetil in postoperative severe -multiple -trauma patients. Methods 117 severe- multiple- trauma patients were carried with anesthesia and emergency operation, were randomly divided into two group, A group was given fentanyl ,then B group was flurbiprofen axetil puls low - dose fentanyl. The differences of analgesic effect between group A and B were compared. Results In the same analgesia condition, the recovery time of breath and consciousness and the time of pulling tube in flubiprofen axetil plus loe dose fentanyl group were shorter than those in fentanyl group However the dose of fentanyl and side - effect were less. Conclusion For postoperative severe - multiple - trauma patients, analgesic treatment by flurbiprofen axetil was benefit for condition observing and early weaning from ventilator, and flurbiprofen axetil was helpful to reduce the dose of fentanyl.

关 键 词：氟比洛芬酯 严重多发伤 芬太尼 镇痛 

分 类 号：R614[医药卫生—麻醉学]