血清肌钙蛋白I和肌红蛋白联合检测在急性心肌梗死早期诊断中的价值  

Vasue of Combined Detection of Cardiac Troponin Iand Myoglobin in the Early Diagnosis of Acute Myocardial Infraction

作　　者：张志虎[1] 张有建 贾志云[1] 

机构地区：[1]青海油田职工总医院急诊科,736202

出　　处：《中国实用医药》2009年第25期25-26,共2页China Practical Medicine

摘　　要：目的探讨心肌肌钙蛋白I（CTnI）、肌红蛋白（Mb）联合检测在急性心肌梗死（AMI）早期诊断中的的应用价值。方法采集56例AMI患者于胸痛发作0～4h、8h、12h、24h、48h、3d、5d和7d的血清，以及对照组48例的空腹血清同步进行cTnI与Mb的动态检测。结果AMI组血清cTnI、Mb的浓度均高于对照组（P〈0．01）。AMI患者的早期0～4hMb的灵敏度明显高于cTnI；而8h以后cTnI的灵敏度和准确度明显高于Mb。结论CTnI、Mb作为心肌损伤的早期标志物联合检测，可提高急性心肌梗死早期诊断的特异性和敏感性。Objective To explore the clinical value of cardiac troponin I （ cTn I） and myoglobine （Mb） in the early diagnosis of acute myocardial infraction （AMI）. Methods The serum eTnI and Mb were detected in 56 AMI patients after they got breast-aeh, and 48 healthy control group at various time phase including 0 - 4 h, 8 h, 12 h ,24 h,48 h,3 days ,5 days and 7 days. Results The levels of serum cTnI and Mb in AMI group were higher than that i＇n the control group. The sensitivity of Mb in the diagnosis of AM 1 was higher than that of cTnl when the AM I occurred in 0-4 hours. However,the sensitivity and accuracy of cTnI in the diagnosis of AMI than that of M b in 8 hours later. Conclusion As the The detection of cTnl combined with Mb.

关 键 词：心肌肌钙蛋白I 肌红蛋白 急性心肌梗死 

分 类 号：R542.22[医药卫生—心血管疾病] R734.2[医药卫生—内科学]