2006～2008年我院质子泵抑制剂的应用分析  

Analysis of proton pump inhibitors used in our hospital during 2006～2008

作　　者：严惠明[1] 余晓霞[1] 刘春霞[1] 余嘉锐[1] 

机构地区：[1]中山大学附属第二医院药学部,广州510120

出　　处：《中国实用医药》2009年第26期59-61,共3页China Practical Medicine

摘　　要：目的对本院质子泵抑制剂的使用情况进行分析,为临床合理、经济高效地使用药物提供参考依据。方法对本院2006～2008年质子泵抑制剂的用药频度(DDDs)、总消耗金额、日治疗费用进行统计,分析。结果奥美使用频率居调查药品中最高,且呈明显上升趋势,平均增幅为162.2%。耐信(20mg)的DDDs排在第二位。DDDs相对靠后的多为药物疗效差异不大,价格偏高的药物,如兰索拉唑(臣邦力威)。奥美的金额序号/DDDs序号的序号比为4.00,序号比最大,表明该药的使用频度较高,但其日治疗费用却相对较低。雷贝拉唑钠肠溶片(安斯菲)的排序比值小于0.5,说明其价格偏高。结论质子泵抑制剂的使用数量和频率呈快速上升状态,表明近年来人们的胃部疾病不断增加,所耗费的治疗金额不断增加。Objective To analyze the proton pump inhibitors used in The Second Affiliated Hospital of Sun Yat-sen University, to provide a reference basis for the clinical, cost-effective use of drugs. Methods The DDDs, the total consumption of the amount of treatment costs and the DDC of proton pump inhibitors from 2006 to 2008 were arelyzend. Results The use frequency of omeprazole was the highest and shows an upward trend, with an average increase of 162. 2%. The DDDs of esomeprazole （20 mg）was in the second place. Because of little difference in drug efficacy, the high price of drugs, the DDDs of drugs feu behind, such as lansoprazole. The ratio of the order of the amount of treatment costs and the DDDs was the maximum,indicating that the use of the drug was more frequency, but the day had a relatively low cost of treatment. The ratio of the order of rabeprazole sodium enteric-coated tablets was less than 0. 5, for its high price. Conclusion The number and frequency of proton pump inhibitors increase rapidly in the state,indicating that people＇ s stomach diseases increase in recent years, increasing the amount of the cost of treatment.

关 键 词：质子泵抑制剂 限定日剂量 用药频度 日治疗费用 

分 类 号：R96[医药卫生—药理学]