钩端螺旋体与宿主细胞相互作用的研究现状  

Research progress on the interaction between the leptospires and host ceils

作　　者：赵聪聪[1] 郭晓奎 姜叙诚[1] 

机构地区：[1]上海交通大学医学院病理学教研室,上海200025 [2]上海交通大学医学院病原生物学教研室,上海200025

出　　处：《公共卫生与临床医学》2009年第3期156-159,共4页Public health and dinical medicine

基　　金：国家自然科学基金课题（NO.30770820）;上海市自然科学基金课题（NO.062R14056）

摘　　要：钩端螺旋体病是一种由致病性钩端螺旋体感染引起的人兽共患病。致病性钩端螺旋体在宿主体内播散过程中与遇到的各种宿主细胞相互作用，这在钩体病的发生发展过程中起到重要作用。本文阐述了近年来国内外有关钩端螺旋体和宿主细胞相互作用，并探讨钩端螺旋体致病机制的研究趋势。Leptospirosis is a zoonotic disease caused by the infection with Leptospira spp. During the pathogenic leptospires dissemination in the host, the interaction between the pathogens and different host cells result in the pathogenesis of the leptospirosis. This paper provides an overview of recent studies on the interaction between the leptospires and the host cells, and also previews the possible research directions for the pathogenesis of the leptospirosis in the future.

关 键 词：钩端螺旋体 宿主细胞 相互作用 

分 类 号：R377.5[医药卫生—病原生物学]