ICU 106株鲍氏不动杆菌感染特点及预防控制  

Infection Characteristic,Prevention and Control of 106 Acinetobacter baumannii Strains in ICU

作　　者：蒋小伟 周杨霄 李国钢 葛鸣俊 万汝根 

机构地区：[1]东阳市人民医院检验科,浙江东阳322100

出　　处：《中华医院感染学杂志》2009年第18期2493-2494,共2页Chinese Journal of Nosocomiology

摘　　要：目的分析ICU中鲍氏不动杆菌的易感因素及其耐药性,探讨鲍氏不动杆菌交叉感染预防控制的新思路及有效方法。方法回顾性分析医院ICU2006年9月-2008年9月鲍氏不动杆菌的感染特点及其体外药敏试验,了解感染危险因素。结果在体外药敏试验中,仅头孢哌酮/舒巴坦和阿米卡星的敏感性较高,分别为65.09%和72.64%,免疫力低下、严重创伤、侵入性操作、使用呼吸机、长时间住院等因素导致ICU中鲍氏不动杆菌严重交叉感染。结论加强环境消毒、加大医务人员医院感染知识的教育、严格执行洗手制度、合理使用抗菌药物、保护易感人群,采用"降阶梯防控策略",对控制ICU鲍氏不动杆菌的交叉感染及防治具有非常重要意义。OBJECTIVE To analyze the susceptible factors and resistance of Acinetobacter baumannii in ICU, in order to create a novel thought of effective prevention and control of A. baumannii cross-infection. METHODS Specimens were collected from ICU patients with infections from Sep 2006 to Sep 2008. The infection characteristic was analyzed and the drug sensitivity was tested to know the risk factors of infection retrospectively. RESULTS The factors of low immunity, severe wound, invasive operation and using ventilator led to the serious cross-infection of A. baumannii in ICU. In vitro drug susceptibility test, the sensitive rates only to cefoperazone/ sulbactam and amikacin were higher. They were 65.09% and 72.64%, respectively. CONCLUSIONS It has great significance in the prevention and control of A. baumannii cross-infection in ICU to strengthen the environment disinfection, were education of nosocomial infection knowledge among medical staff, executeing the hand-washing system strictly, useing the antibiotics rationally, keeping the susceptible crowd and adopting de-escalation strategy of prevention and control.

关 键 词：鲍氏不动杆菌 耐药性 易感因素 防控策略 

分 类 号：R378[医药卫生—病原生物学]