奥沙拉嗪与柳氮磺胺吡啶治疗溃疡性结肠炎59例对比观察  

Olsalazine and SASP therapy in patients with ulcerative colitis clinical study of 59 cases

作　　者：邵景[1] 蒲利华[2] 

机构地区：[1]西安市第一医院消化内科,西安710002 [2]西安市儿童医院

出　　处：《陕西医学杂志》2009年第9期1223-1224,共2页Shaanxi Medical Journal

摘　　要：目的:探讨奥沙拉嗪(Olsalazine)和柳氮磺胺吡啶(SASP)治疗溃疡性结肠炎(UC)的疗效和不良反应。方法:将59例溃疡性结肠炎患者按服用奥沙拉嗪和柳氮磺胺吡啶随机分为两组。对两组的治疗效果和不良反应进行比较。结果:奥沙拉嗪与SASP的治疗效果无显著性差异,但奥沙拉嗪的不良反应明显小于SASP(P<0.05)。结论:奥沙拉嗪适用于需长期服药的UC患者。Objective： To explore the efficacy and the adverse effects of Olsalazine and SASP in the treatment of ulcerative colitis （UC）. Methods： 59 patients with UC were randomly divided into two groups. Olsalazine was used in one of the groups, and SASP was used in the other group. Then the efficacy and the adverse effects of the two groups were observed. Results： There was no significant difference in the efficacy between Olsalazine and SASP, but the adverse effects of Olsalazine was obviously milder than those of SASP. Conclusion： Olsalazine is a suitable choice for UC patients who need long term medication.

关 键 词：结肠炎 溃疡性/药物疗法 氨基水杨酸类/治疗应用 柳氮磺胺吡啶/治疗应用对比研究 

分 类 号：R259.746.2[医药卫生—中西医结合] R574.62[医药卫生—中医内科学]