不同类别切口肿瘤患者围术期预防性应用抗菌药物分析  

Perioperative Prophylactic Use of Antibiotics in Tumor Patients with Different Surgical Incisions

作　　者：陈莲珍[1] 贺飞[1] 马金兰[1] 戴媛媛[1] 田振杰[1] 张培春[1] 盛明宇[1] 蔡宇[1] 刘毅[1] 赵平[1] 

机构地区：[1]中国医学科学院肿瘤医院,北京市100021

出　　处：《中国药房》2009年第26期2010-2013,共4页China Pharmacy

摘　　要：目的:了解不同类别切口肿瘤患者围术期抗菌药物的应用情况。方法:随机抽取我院2007年7月～2008年6月各季度外科肿瘤手术患者出院病历15份,共60份,进行围术期抗菌药物应用统计、分析。结果:切口感染率为0%,抗菌药物应用率达100%,Ⅰ类切口手术平均用药1.5种,疗程4.8d;Ⅱ类1.9种,疗程7.7d。所选药物头孢菌素类占68.3%(41/60),喹诺酮类占41.7%(25/60)。结论:我院不同类别切口手术感染控制较好,但是否都应预防性应用抗菌药物及品种选择有待根据药敏情况作进一步研究。给药时机、应用时间和联合用药情况还需改善。OBJECTIVE： To investigate the status of perioperative prophylactic use of antibiotics in tumor patients with different surgical incisions. METHODS： A total of 60 （15 seasonly） case histories of discharged patients who underwent tumorectomy between Jul.2007 and Jun. 2008 were randomly sampled for statistical analysis in respect of the perioprative prophylactic use of antibiotics. RESULTS： The incisional wound infection rate was 0% ; the ratio of patients using antibiotics was 100%. An average of 1.5 kinds of antibiotics were used and the course of treatment was 4.8 days for type Ⅰ incision versus 1.9 kinds and 7.7 days for type Ⅱ incision. Of the antibiotics used, Cephalosporins represented 68.8% （41/ 60） and Quinolones 41.7% （25/60）. CONCLUSION： The incisional wound infection rate is under good control in our hospital; however, whether perioperative prophylactic use of antibiotics should be applied in all tumor patients and the choice of drug kinds remain to be studied further based on the drug susceptibility. The timing and duration of medication as well as drug combination remain to be improved.

关 键 词：肿瘤患者 围术期 抗茵药物 切口类别 调查研究 

分 类 号：R969.3[医药卫生—药理学] R979[医药卫生—药学]