用紫外分光光度法测定乙醇溶液中依沙吖啶的含量  

Determine the Contend of Ethacridine in Ethanol Solution by UV Spectrophotometric Method

作　　者：李中[1] 刘雪梅[1] 陈兆军[1] 

机构地区：[1]辽宁省大连市儿童医院药剂科,116027

出　　处：《中国实用医药》2009年第27期65-66,共2页China Practical Medicine

摘　　要：目的建立紫外分光光度法测定乙醇溶液中依沙吖啶含量的方法。方法以乙醇为溶剂,在370nm波长处测定溶液的吸光度,计算依沙吖啶的含量。结果在5μg/ml～15μg/ml的范围内吸光度与浓度之间具有良好的线性关系(r=0.9985),平均回收率为100.8%,RSD为1.16%(n=4)。结论该方法方便可靠,可以用于医院制剂的质量控制。Objective To establish method for determining the content of ethacridine in ethanol solution by UV spectrophotometric method. Methods To determine the Abs of ethacridine in ethanol solution at 370nm; then calculate the content of ethacridine. Results There was good linear relationship between Abs and concentration of ethacridine （r = 0. 9985 ） ranging from 5μg/ml - 15μg/ml, with a average recovery rate of 100. 8% and RSD 1.16 percent （n =4）. Conclusion This method is reliable enough for quality control of hospital preparation.

关 键 词：依沙吖啶 紫外分光光度法 含量测定 

分 类 号：R927.2[医药卫生—药学] R284.2