线性扫描极谱法研究布洛芬的电化学行为  

Study on Electrochemical Behavior of Ibuprofen by Linear Scanning Polarography

作　　者：谢天阳[1] 吴粦华[1] 

机构地区：[1]龙岩学院化学与材料学院,龙岩364000

出　　处：《理化检验（化学分册）》2009年第9期1058-1060,共3页Physical Testing and Chemical Analysis(Part B:Chemical Analysis)

基　　金：福建省教育厅自然科学基金项目(JA03165)

摘　　要：采用线性扫描极谱法和循环伏安法研究布洛芬的电化学行为。在pH 2.79B-R缓冲溶液中布洛芬于-1.298 V(vs.SCE)处产生一灵敏的吸附波,在布洛芬质量浓度为10.0～1 000.0 mg·L^(-1)范围内,其一次微分线性扫描峰电流与布洛芬浓度呈线性关系,检出限(3S/N)为5 mg·L^(-1)。对100.0 mg·L^(-1)布洛芬溶液进行6次平行测定,相对标准偏差为1.62%,回收率在96.2%～103.8%之间。试验证实,布洛芬在电极上的还原反应在低扫速时为受扩散控制的不可逆过程,而在高扫速下,还原波是有吸附性的准可逆波。The electrochemical behavior of ibuprofen was studied by linear scanning polarography and cyclic voltammetry. In a B-R buffer solution of pH 2. 79, a sensitive adsorption wave given by ibuprofen was observed at -1. 298 V （vs. SCE）. Linear relationship between values of peak current of 1st derivative plot of linear scanning and mass concentration of ibuprofen in the range of 10. 0-1 000. 0 mg·L^-1 was obtained, with a detection limit （3S/N） of 5 mg·L^-1. Precision of the method was tested at the concentration level of 100. 0 mg·L^-1 for 6 replicate determinations, and the value of RSD found was 1.62%. Recovery of the method was tested by standard addition method, and values of recovery found were in the range of 96. 2%-103. 8%. It was shown that, at a low scanning rate, the reduction of ibuprofen at the electrode is an irreversible process, controlled mainly by diffusion; and at a high scanning rate, the reduction wave is due to quasi-reversible process and behaving with adsorptive property.

关 键 词：布洛芬 线性扫描极谱法 吸附波 

分 类 号：O657.14[理学—分析化学]