妊娠梅毒感染的相关因素及诊治进展  

Correlation Factor of Infection in Pregnancy Syphilis and Advances in Diagnosis and Treatment of Pregnancy Syphilis

作　　者：杨森[1] 李卉[1] 王红艳[1] 

机构地区：[1]安徽医科大学第一附属医院皮肤科,安徽医科大学皮肤病研究所,安徽合肥230022

出　　处：《中国皮肤性病学杂志》2009年第9期595-598,共4页The Chinese Journal of Dermatovenereology

摘　　要：目前,我国妊娠梅毒的发病率呈上升趋势。妊娠期梅毒螺旋体能通过胎盘引起胎儿宫内窘迫,造成胎儿发育不良,甚至死胎。妊娠期梅毒感染的危险因素与发病年龄、文化程度、治疗开始孕周、职业、多性伴史、住址、确诊时TRUST滴度及胎传梅毒的发生有着密切的联系。妊娠梅毒除了对胎儿影响外,孕妇本身常伴有严重的并发症。因此,进一步了解妊娠梅毒的发病、病理生理学与免疫学的改变,明确妊娠与梅毒的相互影响及导致先天梅毒的危险因素,对于有效地控制梅毒的母婴传播,预防和治疗梅毒螺旋体在宫内感染导致的不良后果,降低先天梅毒的发病率具有重要意义。Objective At present, incidence of pregnacy syphilis increase rapidly in our country. During pregnancy, fetal distress through the placenta is caused by treponema pallidum, resulting in dysplasia of fetal or even stillbirth. Infection and risk factors of pregnant syphilis include age, education degree, gestational age, time receiving treatment, occupation, history of many sexual partners, address, time of diagnosis and TRUST titer, all these are closely linkage with congenital syphilis. Pregnancy syphilis apart from the impact of fetus, the pregnant women themselves have often accompanied by serious complications. Thus, it is very necessary to understand syphilis at gestation as its incidence, pathophysiology, immunology, pregnancy and syphilis interaction, risk factors to congenital syphilis, which could effectively control maternal-neonatal transmission and prevent bad pregnant outcomes. There are very important significance for decreasing the incidence of congenital syphilis.

关 键 词：梅毒 妊娠 先天梅毒 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]