超声乳化白内障吸除联合人工晶状体植入术后眼前节相干光断层扫描观察  

Slit lamp optical coherence tomography study of anterior segment changes after phacoemulsification and foldable intraocular lens implantation

作　　者：晏丕松[1] 张振平[1] 林浩添[1] 吴文捷[2] 柏凌[3] 

机构地区：[1]中山大学中山眼科中心,广州510060 [2]福建省立医院眼科 [3]西安交通大学医学院第二附属医院眼科

出　　处：《中华眼科杂志》2009年第9期809-813,共5页Chinese Journal of Ophthalmology

基　　金：广东省科技计划项目（2005830901006）

摘　　要：目的应用裂隙灯显微镜眼前节相干光断层扫描（OCT）观察超声乳化白内障吸除联合人工晶状体（IOL）植入术后眼前节组织的变化情况，探讨手术对眼前节结构的影响。方法前瞻性系列病例研究。使用海德堡公司裂隙灯显微镜眼前节OCT观察40例（44只眼）行超声乳化白内障吸除联合IOL植入术患者术前和术后1d、1周、2周及1个月的眼前节组织变化情况。对所测量的数据进行重复测量设计资料的方差分析，用LSD法进行两两比较。结果中央及切口处角膜在术后第1天全部患者均明显增厚（与术前相比增厚分别为99．59μm,234．57μm；P=0．490），中央角膜厚度至术后1个月可恢复术前水平，而切口处角膜厚度还较术前厚约19．25μm（P=0．001）；前房深度（ACD）和各项反映前房角宽度的指标（AOD500、AOD750、TISA500、TISA750）在术后各观察时间点，均较术前明显加深和加宽（均P〈0．05）；ACD虽在术后2周以内的变化不大（均P〈0．05），但在术后1个月时还尚不能保持稳定；而前房角宽度的变化在术后早期就可基本保持稳定（均P〉0．05）。结论裂隙灯显微镜眼前节OCT可客观、定量评价白内障手术对眼前节形态特征的影响。Objective To investigate quantitative changes of the anterior segment configuration after clear corneal incision phacoemulsification and foldable intraocular lens （IOL） implantation with slit-lampadapted optical coherence tomography （SL-OCT）. Methods In prospective consecutive case series, clear corneal incision phacoemulsification and foldable intraocular lens implantation were performed in 44 eyes of 40 patients. The changes of the anterior segment configuration were performed by SL-OCT before and 1 day, 1 week, 2 weeks and 1 month after surgery. SPSS 16. 0 software was used to analyze statistical difference. Results For all patients, the central corneal thickness （CCT） and the incisional corneal thickness （ICT） increased significantly 1 day after surgery （ CCT increased 99.59μm, ICT increased 234. 57 μm; P = 0. 490）. At 1 month, the CCT almost had returned to baseline, but the ICT had been ticker about 19. 25 μm than baseline （ P = 0. 001 ） . The measurements of ACD, AOD500, AOD750, TISA500, TISA750 also increased significantly 1 day after surgery. Although the ACD had no changes within 2 weeks（ all P 〈 0. 05 ） , it had been not stable. The changes of the width of the anterior chamber had been stable in the early period after surgery（ all P 〉 0. 05 ）. Conclusion The SL-OCT could impersonality and quantificationally evaluate the anterior segment changes induced by cataract surgery.

关 键 词：眼前半段 体层摄影术 光学相干 超声乳化白内障吸除术 晶体 人工 角膜 前房 

分 类 号：R686[医药卫生—骨科学]