1800MHz电磁波辐射出生前暴露对子代大鼠海马脑区超微结构的影响  

Effects of Pregnancy Exposure to 1800 MHz Electromagnetic Irradiation on Hippocampus Ultrastructure of Offspring Rats

作　　者：张媛[1] 武慧欣[1] 李宏玲[1] 周浩[1] 刘松[1] 吴锡南[1] 宋精玲[1] 

机构地区：[1]昆明医学院环境卫生学与职业卫生学系,云南昆明650031

出　　处：《环境与健康杂志》2009年第9期810-811,F0003,共3页Journal of Environment and Health

基　　金：国家自然科学基金资助项目(30460116)

摘　　要：目的探讨1800MHz电磁波辐射出生前暴露对子代大鼠海马脑区超微结构的影响。方法90只Wistar大鼠(雌∶雄为2∶1)合笼,怀孕后孕鼠暴露,并设置相同数量的对照。暴露组大鼠在功率密度分别为0.5和1.0mW/cm2的1800MHz连续电磁场条件下照射;对照组进行虚拟暴露,每天12h,连续照射21d。随机抽取各组出生后3、72d仔鼠3只,制备大脑切片,观察超微结构。结果仔鼠海马脑区神经细胞和毛细血管未见异常,有些暴露组仔鼠海马脑区毛细血管周围轻微水肿,但也见于对照组的部分大鼠。全部切片未见神经细胞凋亡、坏死等病变。结论1800MHz电磁波辐射出生前暴露未对子代大鼠海马脑区超微结构产生异常影响。Objective To study effects of 1 800 MHz electromagnetic field exposure in pregnancy on the uhrastructure of the hippocampus of offspring rats. Methods Ninety Wistar rats （female and male was 2：1） were mated, and the pregnant rats were exposed to 1 800 MHz microwave field with power density of 0.5 mW/cm2 or 1.0 mW/cm2, 12 h/d, for 21 consecutive days, the rats in the control group received dummy exposure. Three rats aged 3 days and 72 days were selected from groups for ultrastructure observation of hippocampus. Results No significant pathological changes were observed in nerve cells and capillary vessels in the hippocampus. Conclusion The results of the present paper indicate that pregnancy exposure to 1 800 MHz electromagnetic field, may not lead to abnormal uhrastructure changes in hippocampus of offspring rats

关 键 词：辐射 超微结构 海马 

分 类 号：R994.6[医药卫生—毒理学]