趋化因子ENA-78与肾脏疾病  

Chemokines ENA-78 and renal disease

作　　者：欧海青[1] 刘春[1] 

机构地区：[1]石河子大学医学院第一附属医院肾病科,新疆石河子832000

出　　处：《现代生物医学进展》2009年第15期2971-2973,共3页Progress in Modern Biomedicine

摘　　要：体外实验中,各种肾脏细胞都能在特定刺激下表达趋化因子及受体。动物模型和人类肾脏疾病的肾组织中,炎症细胞浸润同时出现趋化因子及受体表达增多。ENA-78是一种来源广泛、生物功能多样的趋化因子,通过与其受体相互作用,引起中性粒细胞等白细胞的趋化、活化,参与肾脏疾病的发生、发展。In vitro experiments, various kinds of renal cells expressed chemokine and its receptor under specific stimulation. An- imal models and human renal disease in the renal tissue, inflammatory cell infiltrated at the same time expression of chemokine and its receptor increased. ENA-78 is a source of a wide range of diverse biological functions of ehemokines, through interaction with its recep- tor, causing neutrophil ehemoattractant, such as white blood cells, activated to take part in the occurrence of renal disease, development.

关 键 词：趋化因子 ENA-78 肾病疾病 

分 类 号：R692[医药卫生—泌尿科学]