邻菲啰啉与四氧嘧啶稀土化合物的合成及抑菌作用  

The Synthesis and Antibacterial Property of Rare Earth Compounds with Alloxan and 1,10-Phenanthroline

作　　者：张仲生[1] 吴集贵[1] 邓汝温[1] 李全东[1] 武世界[2] 

机构地区：[1]兰州大学化学系 [2]兰州医学院

出　　处：《兰州大学学报（自然科学版）》1990年第4期69-75,共7页Journal of Lanzhou University(Natural Sciences)

基　　金：国家自然科学基金

摘　　要：本文报道了邻菲啰啉与四氧嘧啶稀土三元化合物的合成方法,通过对组成分析、红外光谱,核磁共振谱、热谱、磁矩和电子光谱等性质确定化合物的组成为 RE·HA·A(phen)_(1·5)·C_2H_5OH·H_2O(RE=La、Ce、Pr、Nd、H_2A 为四氧嘧嘧,phen 为邻菲哕啉)RE·HA·A(phen)_(0·5)·C_2H_5OH·2H_2O(RE=Sm、Eu、Gd、Dy、Ho、Er、Yb、Y).药理实验表明,稀土三元化合物具有较强的抑菌作用.In this paper we report the method of preparation of a series of rare earth compounds with alloxan(H_2A)and 1,10-phenanthroline(phen)inethanol-water solution.As determined by chemical analysis and elementalanalysis the compositions of these compounds are RE·HA·A(phen)_(1·5)·C_2H_5OH·2H_2O(RE=La,Ce,Pr,Nd)and RE·HA·A(phen)_(0·5)·C_2H_5OH.2H_2O(RE=Sm,Eu,Gd,Dy,Ho,Er,Yb,Y).Their solubilities and molarconductance,effective Bohr magneton number,IR,NMR,TG-DTA curves,electronic spectrum have been measured.The antibacterial results showthat these rare earth compounds have a strong antibacterial action.

关 键 词：稀土化合物 邻菲罗啉 四氧嘧啶 

分 类 号：TQ462.91[化学工程—制药化工]