血清抵抗素和白细胞介素18检测预测宫内感染的价值  

The relationships between serum interleukin-18 and resistin for predicting intraamniotic infection

作　　者：颜道雪[1] 班开斌[1] 张洋[1] 黄友敏[2] 何平[2] 

机构地区：[1]济宁医学院附属滕州市中心人民医院妇产科,277500 [2]济宁医学院附属滕州市中心人民医院济宁医学院附属滕州市中心人民医院检验科,277500,277500

出　　处：《中国医师进修杂志》2009年第9期16-18,共3页Chinese Journal of Postgraduates of Medicine

摘　　要：目的检测自细胞介素18（IL-18）和抵抗素在早产妊娠妇女血清中的含量，以探讨上述指标预测宫内感染的价值。方法选取早产妊娠妇女43例作为宫内感染组，选取同期进行产前检查的健康妊娠妇女40例作为对照组。分别抽取空腹静脉血进行IL．18和抵抗素含量的检测。结果宫内感染组IL-18的含量[（38．7±10．4）μg/L]高于对照组[（23．5±5．6）μg/L]，差异有统计学意义（P〈0．01）；宫内感染组抵抗素的含量[（24．84±5．32）μg/L]高于对照组[（17．32±5．15）μg/L]，差异有统计学意义（P〈0．01）；IL-18和抵抗素呈正相关关系（r=0．61，P〈0．01）。结论IL-18和抵抗素的含量在宫内感染的妊娠妇女中存在显著性变化，可作为预测宫内感染的辅助诊断指标。Objective To study the relationships between serum interleukin-18（IL-18） and resisfin for predicting intraamniotie infection. Method Serum levels of IL-18 and resistin were measured in 43 pregnant women with intraamniotie infection （infection group） and 40 normal pregnant women （control group）. Results The level of IL-18 in infection group[ （38.7± 10.4） μg/L] was higher than that in control group [ （23.5 ± 5.6） μg/L], there was significant difference between two groups （P 〈 0.01 ）. The level of resistin in infection group [ （24.84 ± 5.32） μg/L] was higher than that in control group [ （17.32 ± 5.15 ） μg/L], there was significant difference between two groups （P 〈 0.01 ）. The levels of resistin and IL-18 were correlated in pregnant women with intraamniotie infection （r = 0.61, P 〈 0.01 ）. Conclusion Detecting the levels of IL-18 and resistin in pregnant women earl identify intraarnniotie infection.

关 键 词：白细胞介素18 抵抗素 宫内感染 

分 类 号：R714[医药卫生—妇产科学]