紫外分光光度法测定盐酸林可霉素乳膏的含量  

Determination of lincomycin hydrochloride in cream by ultraviolet spectrophotometry

作　　者：除碧雄 刘圣[1] 沈爱宗[1] 施明德[1] 

机构地区：[1]安徽省立医院,合肥230001

出　　处：《中国现代应用药学》1998年第4期41-42,共2页Chinese Journal of Modern Applied Pharmacy

摘　　要：目的:测定盐酸林可霉素乳膏的含量。方法:依据氯化钯与盐酸林可霉素形成稳定络合物,用紫外分光光度法于380nm处测定其吸收度,并计算含量。结果:回收率为99.63％,RSD为0.18％,线性范围为36.56～82.26μg/ml。结论:该方法适合该制剂的含量测定。OBJECTIVE: To determinate the quantity of Lincomycin hydrochloride in its cream. METHODS: According to formed stable complex with PdCl2, Lincomycin hydrochloride was determinated by ultraviolet spectrophotometry. RESULTS: The recovery was 99.63%(RSD= 0.18%) and Linear range was 36.56 - 82.26μg/ml. CONCLUSION: The method was suitable as assay of the preparation.

关 键 词：紫外分光光度法 林可霉素 乳膏 含量测定 

分 类 号：R978.15[医药卫生—药品] R927.2[医药卫生—药学]