Ebselen对耐力训练大鼠GST、CAT和LDH表达的影响  

Action of Ebselen on Expression of GST,CAT,LDH Induced by High-Intensity and Endurance-Training Rat

作　　者：郭飞[1] 刘军[2] 

机构地区：[1]陕西师范大学,西安710062 [2]西安体育学院运动生理学与生物化学教研室,西安710068

出　　处：《西安体育学院学报》2009年第5期585-588,共4页Journal of Xi'an Physical Education University

摘　　要：目的探讨ebselen对运动训练大鼠GST、LDH和CAT表达的影响。方法SD雄性健康大鼠30只,随机分为3组:安静对照组10只、运动对照组10只、运动加药组10只;后两组进行为期8 w的跑台训练,建立大强度耐力训练模型。测定上述相应指标。结果运动服药组大鼠GST、CAT表达提高,LDH表达下降。结论Ebselen对保护运动大鼠细胞膜的完整性有积极意义,对提高机体抗氧化能力具有一定意义。Objective To study the effect of ebselen on the expression of GST, LDH and CAT in the trained-endurance rat. Methods Thirty male healthy SD rats were randomized into 3 groups, namely, the control group（A）, exercise group（B） and exercise added ebselen group（C） with 10 rats in each group. To establish the high-intensity and endurance-trained model for 8 weeks. The contents of LDH, GST and CAT were tested in rat. Results Compared with exercise group, ebselen increased expression of GST and CAT and decreased expression of LDH. Conclusion Ebselen had certain influence on increasing the antioxidant enzyme activity and the stability of cell membrane.

关 键 词：EBSELEN 大强度耐力训练大鼠 GST LDH CAT 

分 类 号：G804.7[文化科学—运动人体科学]