Synthesis and Crystal Structure of 8-(2,3-Dimethoxyphenyl)-10,11,12,13-tetrahydro-9H-benzo[f]cyclohepta[c]quinoline  

作　　者：王香善 李庆 杨科 姚昌盛 

机构地区：[1]School of Chemistry and Chemical Engineering,Xuzhou Normal University

出　　处：《Chinese Journal of Structural Chemistry》2009年第9期1121-1125,共5页结构化学（英文）

基　　金：supported by the National Natural Science Foundation of China (20802061);Natural Science Foundation of the Education Committee of Jiangsu Province (08KJD150019);Qing Lan Project (08QLT001) of the Education Committee of Jiangsu Province

摘　　要：The title compound 8-（2,3-dimethoxyphenyl）-10,11,12,13-tetrahydro-9H-benzo[f]- cyclohepta[c]quinoline （C26H25NO2, Mr = 383.47） was synthesized and characterized by IR, 1H NMR, 13C NMR and elemental analysis. The crystal belongs to triclinic, space group PI with a = 8.1490（16）, b = 9.2550（19）, c = 14.373（3） A, α = 86.96（3）,β= 89.66（3）, γ= 70.32（3）°, Z = 2, V= 1019.2（4） A3, Dc = 1.250 g.cm^-3,μ（MoKα） = 0.078 mm^-1, F（000） = 408, the final R = 0.0555 and wR = 0.1240 for 2228 observed reflections （I 〉 2σ（I））. X-ray analysis reveals that the seven-numbered ring is slightly similar to a six-numbered ring, forming the chairlike conformation. The four rings （Ⅰ, Ⅱ, Ⅲ and Ⅳ） in the benzo[f]cyclohepta[c]quinoline moiety form a screw structure.The title compound 8-（2,3-dimethoxyphenyl）-10,11,12,13-tetrahydro-9H-benzo[f]- cyclohepta[c]quinoline （C26H25NO2, Mr = 383.47） was synthesized and characterized by IR, 1H NMR, 13C NMR and elemental analysis. The crystal belongs to triclinic, space group PI with a = 8.1490（16）, b = 9.2550（19）, c = 14.373（3） A, α = 86.96（3）,β= 89.66（3）, γ= 70.32（3）°, Z = 2, V= 1019.2（4） A3, Dc = 1.250 g.cm^-3,μ（MoKα） = 0.078 mm^-1, F（000） = 408, the final R = 0.0555 and wR = 0.1240 for 2228 observed reflections （I 〉 2σ（I））. X-ray analysis reveals that the seven-numbered ring is slightly similar to a six-numbered ring, forming the chairlike conformation. The four rings （Ⅰ, Ⅱ, Ⅲ and Ⅳ） in the benzo[f]cyclohepta[c]quinoline moiety form a screw structure.

关 键 词：crystal structure benzo[f]cyclohepta[c]quinoline NMR 

分 类 号：O621.3[理学—有机化学]