甲氧沙林脂质体凝胶治疗白癜风的临床疗效观察  

Study on Clinical Effects of Methoxsalen Liposome Gels on Treatment of Vitiligo

作　　者：杨淑清[1] 涂自良[2] 

机构地区：[1]武汉大学人民医院药学部,武汉430060 [2]郧阳医学院附属太和医院

出　　处：《中国药师》2009年第10期1431-1433,共3页China Pharmacist

摘　　要：目的:考察甲氧沙林脂质体(LMOP)凝胶治疗白癜风的疗效。方法:对皮肤科门诊白癜风患者进行病例选择后,以0.075%LMOP凝胶为治疗组,以0.075%甲氧西林(MOP)酊剂为对照组,进行1个疗程(3个月)的治疗。对两组的临床疗效及不良反应进行评价。结果:治疗组显效率为6.67%,总有效率为33.33%。对照组显效率为0%,总有效率为30%。治疗组不良反应发生率为10%,对照组不良反应发生率为80%。结论:与同剂量酊剂相比,LMOP凝胶的疗效提高而不良反应显著降低,值得进一步研究。Objective： To study the clinical effect of mathoxsalen （LMOP）. liposome gel on treatment of vitiligo. Method： The suitable cases were chosen from the patients with leukoderma in department of dermatology. After treated by 0.075% LMOP（ treatment group） or 0. 075% MOP tincture（ control group） for 3 months, the clinical effects and side effects were evaluated. Result： The excellent rate, effective rate and adverse effect rate of treatment group were 6.67% ,33.33%, and 10% , respectively, while those of control group were 0% ,30%, and 80%, respectively. Conclusion. Compare with the control group, LMOP has higher clinical effects and lower side effects,it is valuable to be study further

关 键 词：甲氧沙林 脂质体凝胶 临床疗效 

分 类 号：R758.41[医药卫生—皮肤病学与性病学]