无痛可视人工流产术有效性安全性相关因素研究  

Painless visual effectiveness of induced abortion-related factors of safety

作　　者：娄庆文 于沛涌 刘志刚 陈晓光 娄长瑜 李亚玲 杨晓峰 王亚明 

机构地区：[1]河北省青龙满族自治县生殖保健医院,河北青龙066500 [2]河北省青龙人民医院,河北青龙066500 [3]河北省青龙卫校,河北青龙066500

出　　处：《中国当代医药》2009年第18期12-14,共3页China Modern Medicine

基　　金："河北省人口计生委2009年科研计划课题"项目相关论文。项目编号:2009-A01

摘　　要：目的:研究探索无痛可视人工流产术有效性与安全性之间的相关因素。方法:比较五组麻醉药(瑞芬太尼、瑞芬太尼+丙泊酚、瑞芬太尼+咪唑安定、丙泊酚、丙泊酚+芬太尼)作用时间、止痛效果、副反应及对体温、呼吸、脉搏、血压及血氧饱和度的影响等,严格操作规范,完善各环节工作,总结有效性与安全性之间的相关因素。结果:五组麻醉药中对诱导、手术、苏醒时间和定向力恢复时间以瑞芬太尼+丙泊酚组最佳,镇痛效果显著,差异具有统计学意义,P<0.05;对生命指征的影响以瑞芬太尼+丙泊酚组最小,安全系数最高,经统计学处理,P<0.05。瑞芬太尼+丙泊酚最佳用药量分别为0.9～1.4μg/kg、1.9～2.2 mg/kg。无痛可视人工流产术有效性与安全性之间的相关因素有:手术适应证、全麻药组合及剂量的选择、施术环境及设备的配置、受术者知情同意、手术医生、护士和麻醉医师的责任心及技术水平、术后指导及随访等。结论:无痛可视人工流产术有效性安全性与手术适应证、全麻药组合及剂量的选择、施术环境及设备的配置、受术者知情同意、手术医生、护士和麻醉医师的责任心及技术水平、术后指导及随访等因素有关。Objective ：Painless visual research induced abortion between the efficacy and safety of the relevant factors. Methods：Comparison of five groups of anesthetics （remifentanil, remifentanil ＋ propofol, remifentanil ＋ midazolam, propofol, propofol ＋ fentanyl） time, analgesic effect, side effects and body temperature, respiration, pulse, blood pressure and oxygen saturation of the impact of strict practices, and improve all aspects of the work of summing up between the efficacy and safety of the relevant factors. Results：Five groups on the induction of anesthesia, surgery, recovery time and recovery time to orientation, remifentanil ＋ propofol group was the best, a significant analgesic effect, with statistical significance, P〈0.05; indication of the impact of life to remifentanil ＋ propofol group was the smallest, the highest factor of safety, statistical, P〈 0.05. Remifentanil ＋ propofol dosage were the best 0.9-1.4 ug/kg, 1.9-2.2 mg/kg. Painless visual induced abortion between the efficacy and safety of the relevant factors include： surgical indications, combinations and doses of local anesthetics wide choice of facilities and equipment operation to configure the environment, informed consent by patients, surgeon, nurses and Anesthesiologists sense of responsibility and skill levels, such as postoperative and follow-up guidance. Conclusion ：Painless artificial abortion visual safety and effectiveness of surgical indications, combinations and doses of local anesthetics wide choice of facilities and equipment operation to configure the environment, informed consent by patients, surgeon, nurses and anesthesiologists of the sense of responsibility and technical the level of guidance and follow-up, such as postoperative factors.

关 键 词：人工流产术 瑞芬太尼+丙泊酚 有效性 安全性 相关因素 应用研究 

分 类 号：R714.21[医药卫生—妇产科学]