山莨菪碱用于小儿非气管插管全麻术后催醒的临床观察  

The clinical observation of anisodamine for non-tracheal intubation in children after general anesthesia wake-up

作　　者：李华[1] 刘勇[1] 

机构地区：[1]湖北省丹江口市第一医院麻醉科,湖北丹江口442700

出　　处：《中国当代医药》2009年第18期23-24,共2页China Modern Medicine

摘　　要：目的:观察山莨菪碱用于小儿非气管插管全麻术后催醒的临床效果。方法:60例静脉全麻患儿ASAⅠ～Ⅱ级,随机分为山莨菪碱催醒(A)组与自然苏醒(B)组各30例。所有患儿均采用氯胺酮+异丙酚麻醉。术毕A组静注山莨菪碱0.2 mg/kg,B组待其自然苏醒。结果:山莨菪碱组在催醒后10,20和30 min苏醒率为26.27%,90.00%,100.00%;而自然苏醒组10,20及30 min分别为10.00%,40.00%和86.67%。两组比较A组苏醒时间明显缩短,差异有统计学意义,P<0.01。结论:山莨菪碱用于小儿非气管插管全麻术后催醒,可明显缩短麻醉苏醒时间,催醒效果确切,苏醒期平稳,脉氧饱和度(SpO_2)维持在98%以上,优于自然苏醒组,除短暂的心率加快外未发现其他不良反应,是值得推广的催醒方法。Objective ：To observe the anisodamine for non-tracheal intubation in children after general anesthesia wake-up clinical results. Methods：60 cases of intravenous anesthesia in children with ASA Ⅰ -Ⅱ grade, were randomly divided into anisodamine wake-up （A） group and the natural wake up （B） group, all 30 cases, all children were ketamine ＋ propofol anesthesia. A group of intravenous surgery anisodamine 0.2 mg/kg, B group until natural awakening.Results：The results in the wake-up anisodamine after 10, 20 and 30 minutes to wake up rate of was 26.27%, 90.00%, 100.00%; and that of natural awake group 10, 20 and 30 minutes were 10.00%, 40.00% and 86.67%. A group of two groups was significantly shorter recovery time, the difference was significant,P〈0.01. Conclusion：Anisodamine conclusions for the non-tracheal intubation in children after general anesthesia wake-up could ignificantly shorten the recovery time anesthesia, wake-up effect of the pre- cise, smooth awakening period, SpO2 maintained at more than 98% better than natural awake group, with the exception of short-term heart rate speed up the things not found in other adverse reactions should be the wake-up method of promotion.

关 键 词：山莨菪碱 小儿非气管插管 全麻 催醒 

分 类 号：R614[医药卫生—麻醉学]