氰乙酸乙酯在近临界水中的水解反应  

Hydrolysis of Ethyl Cyanoacetate in Near-critical Water

作　　者：牛延磊[1] 徐雁南[1] 宫欣欣[1] 戴立益[1] 

机构地区：[1]华东师范大学绿色化学与化工上海重点实验室,上海200061

出　　处：《合成化学》2009年第5期540-543,共4页Chinese Journal of Synthetic Chemistry

基　　金：国家科技部"863计划"资助项目(2007AA05Z101)

摘　　要：研究了在近临界水中氰乙酸乙酯(1)无催化剂的水解反应。结果表明,在去离子水11 g,m(1)∶m(H2O)=1∶500,15 MPa及300℃的条件下反应60 min,氰乙酸乙酯可完全分解为乙醇,乙酰胺和乙酸;且在同一实验条件下酯基的水解较腈基容易。Hydrolysis of ethyl cyanoacetate （1） without catalyst in near-critical water was studied. The results showed that 1 was almost converted to alcohol, acetamide and acetic acid in deionized water of ll g[m（1） ：re（H2O） of 1：500] under 15 MPa at 300 ℃ for 60 min, and hydrolysis ability of the ester group was faster than that of the nitrile group.

关 键 词：氰乙酸乙酯 近临界水 水解反应 

分 类 号：O643.3[理学—物理化学]