急性颅脑损伤患者动态心电图及心肌酶变化分析  

Changes of dynamic ECG and myocardial enzymes in patients with acute brain injury

作　　者：高燕[1] 李京生[1] 郭彩霞[1] 张利环[1] 杜凤和[1] 

机构地区：[1]首都医科大学附属北京天坛医院,北京100050

出　　处：《山东医药》2009年第36期3-5,共3页Shandong Medical Journal

基　　金：国家自然科学基金资助项目(C03030201)

摘　　要：目的观察急性颅脑损伤患者伤后动态心电图的改变和各种与心肌相关的酶学指标的变化,了解急性颅脑损伤所致心肌损害的临床表现特点。方法178例急性颅脑损伤患者,分别于入院即刻和入院1周行24 h动态心电图监测;对其中80例患者于入院即刻行血生化检查。结果急性颅脑损伤患者伤后出现多种心电异常,在入院24 h内表现显著,总发生率为83.15%,之后随着时间的推移明显恢复。急性颅脑损伤患者伤后血CK、CK-MB、LDH、HBDH水平显著升高,且与患者病情轻重程度密切相关。结论急性颅脑损伤患者存在不同程度的心肌损伤,且与患者脑外伤不同的损伤程度密切相关。Objective To observe the alterations of dynamic ECG and various indexs of myocardial enzymology in acute brain injury patients.Methods A total of 178 patients with acute brain injury accepted dynamic ECG monitoring immediately and one week after admission,respectively.Eighty of them underwent blood biochemical tests immediately after admission.Results Multiple anomalous ECG were found in 83.15% acute brain injury patients and were obvious abnormal within 24 h after admission.The level of blood CK,CK-MB,LDH, HBDH was significantly increased after acute brain injury and was closely related to the damage degree of the injury condition. Conclusion There were different degree of myocardial damage in patients with acute brain injury and the myocardial damage maybe closely correlated with the degree of traumatic brain injury.

关 键 词：颅脑损伤 心脏损害 动态心电图 肌酸激酶 

分 类 号：R651.15[医药卫生—外科学]