加味消风散治疗慢性荨麻疹疗效观察及对血清嗜酸粒细胞计数的影响  

Therapeutic Effect of Modified Xiaofeng Powder for Chronic Urticaria and Its Influence on Serum Eosinophil Count

作　　者：温炬[1] 陈宝田[1] 曾抗[2] 兰海梅[2] 林中方[3] 

机构地区：[1]南方医科大学附属南方医院中医科,广东广州510515 [2]南方医科大学附属南方医院皮肤科,广东广州510515 [3]珠海市人民医院皮肤科,广东珠海519000

出　　处：《新中医》2009年第10期33-34,共2页New Chinese Medicine

基　　金：广东省科技计划资助项目(编号:2008B030301162);广东省中医药局基金资助项目(编号:2008210)

摘　　要：目的:观察加味消风散治疗慢性荨麻疹的临床疗效及其对血清嗜酸粒细胞计数的影响。方法:将60例患者随机分为2组各30例,治疗组以加味消风散治疗;对照组以西替利嗪片、赛庚啶片、雷尼替丁片治疗。观察2组治疗效果,并检测治疗组治疗前后血清嗜酸粒细胞计数变化。结果:总有效率治疗组为80.0%,对照组为76.7%,差异无显著性意义(P>0.05)。复发率治疗组为41.7%,对照组为60.9%,差异有显著性意义(P<0.05)。治疗组治疗后血清嗜酸粒细胞计数显著下降,治疗前后比较,差异有显著性意义(P<0.05)。结论:加味消风散治疗慢性荨麻疹有良好的临床疗效,降低患者血清嗜酸粒细胞计数可能是其作用机理之一。Objective:To observe the therapeutic effect of Modified Xiaofeng Powder(MXP) for chronic urticaria and its influence on serum eosinophil count.Methods:Sixty chronic urticaria patients were equally randomized into the treatment group and the control group.The therapeutic effect was evaluated after treatment and the changes of serum eosinophil count before and after treatment were observed.Results:The total effective rate was 80.0%in the treatment group and was 76.7%in the control group,the difference being insignificant between the two groups(P>0.05). The recurrence rate was 41.7%in the treatment group and 60.9%in the control group,the difference being significant between the two groups(P<0.05).The serum eosinophil count before treatment differed from that after treatment(P<0.05).Conclusion:MXP exerts a certain effect for the treatment of chronic urticaria,and one of its therapeutic mechanism may be related with the decrease of serum eosinophil count.

关 键 词：慢性荨麻疹 加味消风散 嗜酸性粒细胞 

分 类 号：R758.24[医药卫生—皮肤病学与性病学]