矽宁抑制血管通透性炎症反应的作用  

Suppressive Effect of Vascular Permeability Inflammation Response

作　　者：宋志芳[1] 陈苘[1] 陈雅萍[1] 

机构地区：[1]浙江医科大学公共卫生学院,310013

出　　处：《职业卫生与病伤》1998年第3期133-135,共3页Occupational Health and Damage

摘　　要：目的：探讨矽宁对血管通透性炎症反应的抑制作用。方法：以二甲苯致炎法和醋酸致腹膜炎法。结果：7、14、28、56mg／kg4个剂量组的血管通透性炎症反应程度受到不同程度的抑制，与对照组相比，差异有非常显著意义（P＜0．01），且矽宁剂量与血管通透性炎症反应的抑制程度呈剂量一效应关系。结论：矽宁对二甲苯致炎法和醋酸所致血管通透性炎症反应有一定的抑制作用。Objectivea:To study the suppressive effect of Xining on vascular permeability inflamma tion reaponse. Method: The inflammation model due to xylene and the peritonitis due to aceticacid. Results:The vascular permeability inflammation responses in 4 test groups (doses of Xiningwere 7, 14, 28 and 56mg/kg)were lower than the control group (P＜0. 01). There was a dose-effectrelationship between dose of Xining and the suppressive degree of inflammation response. Conclu-sion:Xining has suppressive effect on vascular inflammation response due to xylene and acetic acid.

关 键 词：矽宁 矽肺 抗炎作用 治疗 药理 

分 类 号：R135.2[医药卫生—劳动卫生]