早产儿肠外营养方法的对比研究  

Comparative study of parenteral nutrition in premature infants

作　　者：邵新环[1] 罗延峰[1] 杨绍燕 

机构地区：[1]新疆石河子市人民医院儿科,新疆石河子832000

出　　处：《临床儿科杂志》2009年第9期833-836,共4页Journal of Clinical Pediatrics

基　　金：新疆石河子市卫生科研基金资助项目(No.2006YL02)

摘　　要：目的探讨早产儿应用早期及传统两种肠外营养方法的疗效。方法不能耐受全胃肠道喂养的早产儿60例(胎龄28～36周,体质量1200～2500g),随机分为两组,早期组于生后24h以后添加氨基酸及脂肪乳;晚期组采用传统的肠外营养方法,即72h以后应用氨基酸及脂肪乳,同时均根据病情尽早经口微量喂养。两组患儿均于生后第1天与第7天检测血肝功能、总胆红素、三酰甘油、总胆固醇、尿素氮,每天监测体质量、微量血糖。比较两组患儿恢复至出生体质量时间、体质量下降幅度、第3天热量、第7天热量、肠外营养时间、住院天数、过渡到全肠道营养的时间、并发症发生例数及血清胆固醇、三酰甘油、胆红素、尿素氮的变化。结果早期组患儿恢复至出生体质量时间较晚期组短(P<0.01),第3天热量、第7天热量较晚期组高(P<0.01),体质量下降幅度、并发症发生例数两组差异无统计学意义(P>0.05);两组患儿生后相同日龄测得的总胆红素、直接胆红素、总胆固醇、三酰甘油及尿素氮差异均无统计学意义(P均>0.05)。结论早期积极规范的肠外营养支持对早产儿是有益且安全的。Objective To investigate the effects of two parenteral nutrition methods（early nutrition group and later traditional nutrition group） . Methods Sixty premature infants（gestational age between 28 and 36 weeks,birth weight between 1 200 and 2 500 g） who could not tolerate full enteral feeding were randomly divided into two groups. Early nutrition group was fed by amino acids and fat emulsion 24 hours after birth. Later nutrition group was treated with the traditional method of parenteral nutrition,received amino acids and fat emulsion 72 hours after birth. According to the conditions,two groups received minimal-feeding orally. Body weight was monitored everyday,liver function,total bilirubin,triglyceride,total cholesterol,blood urea nitrogen,capillary blood glucose were checked at first and the seventh day after birth. Time returning to birth weight,weight loss rate,the calorie sat the third and the seventh day,duration of parenteral nutrition,duration of hospitalization,time of transition to full enteral feeding,cases with various complications,cases with changes of serum cholesterol,triglyceride,bilirubin and urea between the two groups were recorded. Results In comparison with the later nutrition group,time returning to birth weight was shorter,the calorie at the third and the seventh days were higher in early nutrition group（P 〈 0.01） ,while there were no significant differences in the weight loss rate,incidence of complication between two groups（P 〉 0.05） . Differences in total bilirubin,direct bilirubin,total cholesterol,triglyceride,and blood urea nitrogen were not significant between two groups（P 〉 0.05） . Conclusions Early aggressive and strict parenteral nutritional support is useful and safe for preterm infants.

关 键 词：早产儿 肠外营养 早期 

分 类 号：R722.6[医药卫生—儿科]