心电间期序列归一化直方图的构造方法及其在评价心力衰竭中的应用  

CONSTRUCTION METHOD FOR NORMALIZED HISTOGRAM OF RR SEQUENCE AND ITS APPLICATION FOR EVALUATION HEART FAILURE

作　　者：刘澄玉[1] 刘常春[1] 张庆广[1] 李桥[2] 

机构地区：[1]山东大学控制科学与工程学院,济南250061 [2]山东大学医学院,济南250012

出　　处：《生物物理学报》2009年第4期299-304,共6页Acta Biophysica Sinica

基　　金："863"国家高技术研究发展计划项目(2006AA02Z4D9)~~

摘　　要：提出了一种新的心率变异性分析方法——心电间期序列归一化直方图,并将其应用于受测者心力衰竭的评价。首先采集受测者约5min的心电信号,获取心电间期序列,然后构造出心电间期序列归一化直方图,在此基础上定义了两个指标:中心-边缘比(center-edge ratio,CER)和累积能量(cumulative energy,CE),最后通过对16例心力衰竭组和30例健康对照组的比较得出:指标CER和CE对两组有良好的区分度,其在定量评价心力衰竭程度上有较好的应用价值。A new method for heart rate variability （HRV） analysis, normalized histogram of RR sequence, was proposed and applied to evaluate the heart failure of the subjects. Firstly, RR sequence was obtained from ECG signal which was recorded for about 5 minutes. Then the normalized histogram of RR sequence was constructed. Moreover, the center-edge ratio （CER） and cumulative energy （CE） were defined. According to experiments on the heart failure group （16 subjects） and health control （30 subjects）, it showed that CER and CE were excellent of group discrimination and valuable in evaluating the heart failure level quantitatively.

关 键 词：心电间期序列归一化直方图 心率变异性 中心-边缘比 累积能量 

分 类 号：R318[医药卫生—生物医学工程]