多层螺旋CT甲状腺体积测量的可重复性评价  

THE REPRODUCIBILITY OF THYROID GLAND VOLUMETRY USING MULTI-SLICE SPIRAL CT

作　　者：叶述良 虞德才 罗锦红[1] 张昭全 

机构地区：[1]富顺县人民医院放射科 [2]富顺县晨光医院放射科,四川自贡643200

出　　处：《泸州医学院学报》2009年第5期515-518,共4页Journal of Luzhou Medical College

摘　　要：目的:评价多层螺旋CT甲状腺体积测量的可重复性和一致性。方法:25例颈部螺旋CT扫描患者,扫描数据传输至工作站进行甲状腺体积重建、测量。3位有经验的放射科医生独立进行,每位观察者对所有患者均测量两次。观察者内的差异用配对t检验进行比较,观察者间的差异用重复测量的方差分析比较,相互关系用组内相关系数(intraclass correlation coefficient,ICC)描述,P<0.05为有统计学意义。结果:观察者1两次测得甲状腺平均体积为(12.11±5.42)cm3和(12.04±5.43)cm3.t=1.664,P=0.109,ICC=0.9992,P=0.00。观察者2两次测量的平均体积为(12.09±5.45)cm3和(12.07±5.43)cm3.t=0.445,P=0.661,ICC=0.9991,P=0.00.观察者3两次测量的平均体积为(12.09±5.42)cm3和(12.16±5.46)cm3.t=1.282,P=0.212,ICC=0.9989,P=0.00.3个观察者所测体积的均值分别是(12.07±5.42)cm3、(12.08±5.44)cm3和(12.12±5.44)cm3.F=1.556,P=0.222,ICC=0.9996,P=0.00。结论:螺旋CT甲状腺体积测量具有较高的可重复性和一致性。Objective：To evaluate the reproducibility and agreement of multi-slice spiral computed tomography （CT） in measuring thyroid volume. Methods：Unenhanced spiral CT scan of neck and upper mediastinum was obtained in 25 patients. Thyroid volumes were measured by three observers with 5 years of CT experience of using reconstructed images in CT workstation. Intraobserver variability was calculated using paired-samples t-test and interobserver variability was calculated using analysis of variance of repeated measure. Their agreement was measured using the intraclass correlation coefficient （ICC）. Results：The mean thyroid volume in the two temporally separate observations of the same observer 1 was （ 12.11 ±5.42） cm^3 and （ 12.04±5.43 ） cm^3, respectively, t= 1.664,P= 0.109, ICC=0.9992, P=0.00. The mean thyroid volume in observer 2 was （12.09±5.45）cm^3 and （12.07±5.43）cm^3, respectively, t=0.445,P=0.661 ,ICC=0.9991, P=0.00. The mean thyroid volume in observer 3 was（12.09±5.42）cm^3 and（12.16±5.46）cm^3, respectively, t=1.282 ,P=-0.212, ICC=0.9989, P=0.00. The mean thyroid volume from the two temporally separate observations of the three observers was （ 12.07±5.42 ）cm^3, （ 12.08±5.44 ）cm^3 and （12.12±5.44） cm^3, respectively. F=1.556,P=0.222,ICC=0.9996,P=0.00. Conclusion：The reproducibility and agreement of multi-slice spiral CT in measuring thyroid volume are very high.

关 键 词：甲状腺 计算机X线体层摄影 体积 可重复性 

分 类 号：R814.42[医药卫生—影像医学与核医学]