镍铬烤瓷合金的生物性能  

Biological performance of Ni-Cr porcelain alloy

作　　者：沈晴昳 李国强 钟群 

机构地区：[1]上海市口腔病防治院口腔修复科,上海市200031

出　　处：《中国组织工程研究与临床康复》2009年第38期7555-7558,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

摘　　要：镍铬烤瓷合金的生物学性能与材料所释放的金属离子密切相关。镍铬烤瓷合金所释放的金属离子,尤其是镍、铍等可能导致临近牙周组织和口腔黏膜的炎症反应。体外实验证明,金属过敏反应为多种金属离子对机体免疫系统的影响所致重铸镍铬烤瓷合金的耐腐蚀性差和细胞毒性大。严格按工艺要求制作的镍铬合金烤瓷修复体生物安全性能良好。镍铬烤瓷合金在口腔内腐蚀过程中释放少量金属离子,刺激局部组织,可能导致邻近组织过敏、变色,但对全身系统无明显毒副作用,无明显遗传毒性或致癌性。Biological performances of Ni-Cr porcelain alloy are highly correlated with released metallic ions. Released metal ions from Ni-Cr porcelain alloy, particularly Ni, Be can induce inflammation of the adjacent periodontal tissue and oral mucosa. In vitro evidence has indicated that the immune response can be altered by various metal ions. Allergic reactions due to metallic dental restorations have been documented. Ni has especially been identified as being highly allergenic. The cytotoxicity and corrosion level of Ni-Cr porcelain alloy is increased after recasting. The Ni-Cr porcelain alloy produced according to technology requirements has good biological safety. Ni-Cr porcelain alloy released a few of metal ions which might induce allergy and density of adjacent periodontal tissues, for the stimulation effect of these metal ions. There is no evidence to suggest that Ni-Cr porcelain alloy restorations has systemic toxicity or carcinogenic/genotoxic effect to human.

关 键 词：镍铬合金 烤瓷合金 生物性能 腐蚀 

分 类 号：R318[医药卫生—生物医学工程]