基于表面等离子体激元共振的葡萄糖光化学传感器的研究  

Optical Chemical Glucose Sensor Based on Surface Plasmon Resonance

作　　者：赵晓君[1] 王珍[1] 梁枫[1] 曹彦波[1] 张寒琦[1] 金钦汉[1] 许汉英[2] 

机构地区：[1]吉林大学化学系,长春130023 [2]吉林省进出口商品检验局,长春130062

出　　处：《分析化学》1998年第11期1320-1323,共4页Chinese Journal of Analytical Chemistry

基　　金：厦门大学国家教委材料和生命过程分析科学开放研究实验室基金

摘　　要：采用自行设计组装的表面等离子体激元共振光化学传感器实验装置，在不加其它化学试剂的条件下，研究了传感器对葡萄糖溶液的响应特性。实验结果表明，此传感器测定葡萄糖溶液的稳定性、可逆性良好，响应迅速，使用寿命长。在波长６２０ｎｍ处，灵敏度为２．４× １０－４折射率单位，ＲＳＤ＝１．５％（ｎ＝１１， ０．９２％的葡萄糖）。分析了一些实际样品，结果良好。A novel optical chemical glucose sensor based on surface plasmon resonance (SPR) is presented. Unlike traditional SPR sensor, which was working at a fixed wavelength and with modulated angle of incidence light, the sensor presented was designed on the basis of fixing angle of incidence light and measuring reflected light intensity in the wavelength range of 400 - 800 um. Because no chemical reagent was needed, the sensor was very suitable for the determination of glucose in its injection solution. The sensitivity of the sensor to the refractive index changes was found to be 2 .4 × 10-4 index of refraction units at the wavelength of 620 um. Some samples were analyzed with the sensor. The results obtained were in good agreement with those obtained with the standard method. Under the selected experimental conditions, the sensor has a good repeatability for the determination of 0. 92% glucose solution (n = 11, RSD = 1. 5% ).

关 键 词：SPR 光化学 传感器 葡萄糖 分析 

分 类 号：Q532.303[生物学—生物化学] O629.112[理学—有机化学]