急性心肌梗死患者介入治疗前后心肌血流灌注及心功能变化的临床研究  

Clinical study of the variances in myocardial perfusion tomography and ventricular function in patients undergoing percutaneous coronary intervention

作　　者：龙飞[1] 江珊[1] 杨军[1] 

机构地区：[1]锦州市中心医院心内科,辽宁省121000

出　　处：《中国心血管病研究》2009年第3期168-170,共3页Chinese Journal of Cardiovascular Research

摘　　要：目的通过门控单光子发射计算机显像（GSPECT）检查，探讨急性心肌梗死（AMI）患者介入治疗前、后心肌血流灌注及心功能的变化。方法选择AMI并行介入治疗的患者40例，根据介入术前GSPECT测定的左室射血分数（EF）分为A、B两组（各20例）。在介入治疗前及治疗后4周行GSPECT检查，测定左室功能并评价心肌局部血流灌注。结果介入治疗前、后比较，各项心功能指标均有明显改善，心输出量分别为（4．52±0．44）L／min和（4．89±0．87）L／min（P〈0．01），左室EF分别为（49．23±3．89）％和（55．37±5．57）％（P〈0．01）。A组与B组比较，介入治疗后心肌血流灌注改善率明显较高（38．1％比13．7％，P〈0．01）。结论AMI患者介入治疗后GSPECT检测的心功能各项指标均有不同程度的改善，左室功能正常组介入治疗后GSPECT心肌血流灌注改善更明显。Objective Using the gated single-photon emission computerized tomography （GSPECT） to evaluate the variety of the left ventrieular function and myocardial perfusion on acute myocardial infarction （AMI） patient of undergoing the percutaneus coronary intervention （PCI） therapy. Methods 40 patients with AMI and underwent PC] were chosen. On the base of left ventrieular ejection fraction （EF） before PCI, they were divided into Group A （EF≥50%, n=20）, and group B （EF〈50%, n=20）. The patients were tested by GSPECT before PCI and at 4 weeks after PCI, cardiac functions and myocardial perfusion tomography were analyzed. Results The cardiac functions showed significant improvement after the PCI therapy [（4.52±0.44）L/min vs （4.89±0.87） L/min,P〈0.01 ]. The improvement rate of myocardial segments＇ perfusion in Group A was significantly higher than group B（38.1% vs 13.7%,P〈0.01）. Conclusion The cardiac functions in patients with AMI have improved after PCI. The group possessing normal cardiac function have improved more in myocardial perfusion than that possess- ing abnormal cardiac function after PCI.

关 键 词：心肌梗死 心室射血分数 单光子发射计算机显像 介入 

分 类 号：R541.4[医药卫生—心血管疾病]